中国寄生虫学与寄生虫病杂志 ›› 2007, Vol. 25 ›› Issue (5): 19-433.

• 研究简报 • 上一篇    下一篇

金华哮喘患儿的尘螨过敏测定

赵仕勇;韦翊;李小兵;陈菊萍;包云光;张静   

  1. 浙江金华市中心医院儿科,金华 321000
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-10-30 发布日期:2007-10-30
  • 通讯作者: 赵仕勇

Prevalence of Mite Hypersensitivity in Children with Asthma

ZHAO Shi-yong;WEI Yi;LI Xiao-bing;CHEN Ju-ping;BAO Yun-guang;ZHANG Jing   

  1. Pediatric Department,Jinhua General Hospital,Jinhua 321000,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-10-30 Published:2007-10-30
  • Contact: ZHAO Shi-yong

摘要: 2005年10月~2006年9月,采用皮肤点刺试验测定并比较金华地区哮喘患儿对户尘螨、粉尘螨及热带剥爪螨(热尘螨)等3种尘螨变应原的反应性。结果显示哮喘患儿对户尘螨、粉尘螨变应原的阳性率分别为80.6%、77.8%,其中强阳性分别占65.5%和64.3%;热尘螨的阳性率为61.1%,低于户尘螨和粉尘螨(χ2=21.39, P<0.05),且几乎无强阳性者。热尘螨阳性者对户尘螨、粉尘螨变应原的阳性率分别高达100%(44/44)和95.9%(42/44);热尘螨阴性者对户尘螨、粉尘螨变应原的阳性率均为28.6%(8/28)。结果表明户尘螨、粉尘螨是金华地区儿童哮喘的重要变应原,该组患儿对热尘螨的阳性率61.1%不能排除户尘螨、粉尘螨变应原交叉反应的干扰。

关键词: 儿童, 哮喘, 螨变应原, 皮肤点刺试验

Abstract: By skin prick test, three kinds of mite allergens (Dermatophagoides pteronyssinus Dermatophagoides farinaeBlomia tropicalis) were tested in a group of asthma children in Jinhua area from Oct 2005 to Sep 2006. The pos-rate to allergen from D. pteronyssinus and D. farinae was 80.6% and 77.8% respectively, higher than that of Blomia tropicalis (61.1%) (χ2=21.39, P<0.05). Cases positive to Blomia tropicalis allergen showed 100% and 95.9% positive reac-tion to D. pteronyssinus and D. farinae repectively. The results demonstrated that the important allergens for children′s asthma are from D. pteronyssinus and D. farinae, while the Blomia tropicalis allergen is supposed to have cross-reactivity with the former two mite allergens.

Key words: Child, Asthma, Mite allergen, Skin prick test