中国寄生虫学与寄生虫病杂志 ›› 1987, Vol. 5 ›› Issue (1): 42-44.

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伯氏疟原虫对小鼠红系造血祖细胞作用的实验研究

张易虹   

  1. 第二军医大学放射医学教研室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1987-02-28 发布日期:2017-01-12

EXPERIMENTAL STUDY ON THE EFFECT OF PLASMODIA ON ERYTHROID COLONY FORMING UNIT (CFU-E)

  • Received:2017-01-12 Revised:2017-01-12 Online:1987-02-28 Published:2017-01-12

摘要: 本文观察了小鼠感染伯氏疟原虫AN KA株后,骨髓和脾脏红系造血祖细胞生成由8个以上红系细胞组成的集落(Erythroid Colony Forming Unit CFU-E)的动态变化过程;比较了正常小鼠与感染小鼠骨髓与脾脏CFU-E的生长曲线;证明疟原虫对CFU-E无明显抑制作用。

关键词: 伯氏疟原虫, 实验研究, 祖细胞, 恶性疟原虫, 红系造血, 正常小鼠, 甲基纤维素, 裂殖子, 造血干细胞, 原始红细胞

Abstract: The dynamic process of the bone marrow and spleen CFU-E from the mice infected with Plasmodium berghei was observed and the growing curve of CFU-E of infected mice was compared with that of normal mice. Results revealed no significant suppressive effect on CFU-E by P. berghei infection. It is indicated that the maturity and differen-tiation of erythrocytes were the foundation of invasion and parasitism by merozoites.