中国寄生虫学与寄生虫病杂志 ›› 2019, Vol. 37 ›› Issue (1): 92-96.doi: 10.12140/j.issn.1000-7423.2019.01.017

• 综述 • 上一篇    下一篇

螺类寄生虫感染相关基因表达的研究进展

岳志远(), 郭云海, 秦志强, 张仪*()   

  1. 中国疾病预防控制中心寄生虫病预防控制所,国家热带病研究中心,世界卫生组织热带病合作中心,科技部国家级热带病国际联合研究中心,卫生部寄生虫病原与媒介生物学重点实验室,上海200025
  • 收稿日期:2018-10-10 出版日期:2019-02-28 发布日期:2019-03-18
  • 通讯作者: 张仪
  • 作者简介:

    作者简介:岳志远(1993-),男,硕士研究生,从事福寿螺适应性研究。E-mail: 1069147741@126.com

  • 基金资助:
    国家重点研发计划项目(No. 2016YFC1200500),上海市公共卫生第四轮三年行动计划 (No. GWIV-29)

Research progress on snail gene expression associated with parasite infections

Zhi-yuan YUE(), Yun-hai GUO, Zhi-qiang QIN, Yi ZHANG*()   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China
  • Received:2018-10-10 Online:2019-02-28 Published:2019-03-18
  • Contact: Yi ZHANG
  • Supported by:
    Supported by the National Research and Development Plan of China(No. 2016YFC1200500) and the Fourth Three?year Action Plan of Shanghai Public Health(No. GWIV-29)

摘要:

螺类隶属于软体动物,广泛分布于陆地、淡水和海洋。部分螺类可作为传播寄生虫的媒介宿主,危害人类健康。目前有关螺类感染寄生虫后差异表达基因的研究报道较少,但这些差异表达基因在揭示螺类与寄生虫之间的相互作用、螺类的免疫防御机制方面具有重要作用。本文综述了螺类感染寄生虫后差异表达基因的研究进展,以期为防治螺类传播疾病的相关研究提供参考。

关键词: 螺类, 寄生虫, 感染, 差异表达基因

Abstract:

Snails belong to mollusk invertebrate animals widely distributed on land, in fresh and sea water. Some types of snail are the important intermediate hosts of some helminths and the vectors transmiting parasite infections to human. It has been noticed that snails express some specific genes that are associated with the infection of parasite larvae. The differential expression of genes before and after infection of some parasites plays an important role in the interaction between snails and parasites, as well as the sail’s immune defense against parasite infection. This paper reviews the research progress on the differential expression of genes in snails associated with parasite infection, in order to provide references for the related research on the control of snail and snail-transmitted parasitic diseases.

Key words: Snail, Parasites, Infection, Differential gene expression

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