CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2018, Vol. 36 ›› Issue (1): 15-20.

• CONTENTS • Previous Articles     Next Articles

Analysis on disease burden of hydatid disease in China

Meng-yuan ZHANG1,2, Wei-ping WU2,*(), Ya-yi GUAN2, Li-ying WANG2, Yan-yan HOU3, Yu FENG4, Jun-ying MA5, Qian WANG6, Ying WANG2, Shuai HAN2, Chui-zhao XUE2, Wen-ting WU2   

  1. 1 Shanghai Longhua Hospital, Shanghai 200032, China
    2 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China
    3 The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region, Urumuqi 830002, China
    4 Center for Disease Control and Prevention of Gansu Province, Lanzhou 730000, China
    5 Qinghai Provincial Institute of Endemic Disease, Xining 810000, China
    6 Center for Disease Control and Prevention of Sichuan Province, Chengdu 610041, China
  • Received:2017-12-29 Online:2018-02-28 Published:2018-03-14
  • Contact: Wei-ping WU E-mail:wu_wpipd@163.com

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Abstract:

Objective To define the disability weight and estimate disease burden of hydatid disease in China. Methods A hospital on hydatid disease was selected in each of the four provinces（Autonomous region） of Gansu, Qinghai, Sichuan, and Xinjiang, from December, 2016 to March, 2017. All inpatients admitted within 1 month were surveyed in each hospital. Two counties with hydatid disease prevalence were selected from each province, and in each county 25 cases of hydatid disease were selected to reach a total of 200 cases. A questionnaire was compiled based on International Classification of Functioning, Disability and Health and the MOS 36 item short form health survey, SF-36, to examine the life quality and analyze disability weights of patients. The disease burden was calculated based on the prevalence, number of patients, disability weights and demography data. Results In Gansu, Qinghai, Sichuan, and Xinjiang Province（Autonomous region） , 76, 95, 79 and 89 questionnaires were received, of which 76, 91, 79, and 88 were valid questionnaires, with a recovery efficiency of 98.53%. Of these questionnaires, 46.4% were from males, and 53.6% from females, with an average age of 45.15 (4-79). Of these patients, 73.65% (246/334) were cases of cystic echinococcosis (CE), 24.85% (83/334) were alveolar echinococcosis(AE), and 0.15%(5/334) were unclassified. The morbidity level of the disease was devided into asymptomatic, mild, medium, severe, and death, which accounted for 40.58%, 40.88%, 10.80%, 5.26% and 2.49%, respectively. The average quality score of patients was 0.716, CE being 0.735 and AE being 0.661 (t = 5.464, P < 0.01 CE vs. AE). The life quality score was 0.739 in male, and 0.696 in female (t = 2.986, P < 0.01). The disability weights of those asymptomatic, mild, medium, severe, and death cases were 0.257, 0.280, 0.359, 0.363 and 1, respectively, with an average of 0.302. The years lived with disability(YLDs) were 1.864 per patient. It was 1.864 for CE patients, for AE patients(t = 6.669, P < 0.01). It was estimated that the disease burden of hydatid disease in China added up to 322.4 thousand disability adjusted life year(DALYs), 293.4 thousand YLDs, 28.8 thousand years of life lost（YLLs). Conclusion Echinococcosis is widely prevalent with a heavy disease burden and an enormous threat to the people’s health in the country.

Key words: Echinococcosis, Disease burdun, Disability weight

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