Evaluation of the comprehensive control effects on echinococcosis in Ganzi Prefecture,Sichuan Province from 2016 to 2019

doi:10.12140/j.issn.1000-7423.2021.02.004

Abstract

Abstract:

Objective To evaluate the comprehensive control effects on echinococcosis in Ganzi Prefecture , Sichuan Province, from 2016 to 2019. Methods From 2016 to 2019, comprehensive prevention and control measures, including screening for echinococcosis, deworming and monitoring of infection in dogs, and surveillance of cattle serum antibody, were carried out in 18 counties of Ganzi Prefecture. Ultrasound examination was performed in more than 90% of the residents (aged over 2 years in residence for at least 6 months) to screen for echinococcosis. To investigate the infection rate in dog feces, 4-6 townships were randomly selected from each county in each year of 2016—2019, and no less than 50 samples of dog feces were randomly collected from each township using ELISA for Echinococcus coproantigen. Meanwhile, 4-6 townships were randomly selected from each county in each year of 2016, 2017 and 2019, and 50 yak blood samples were collected from each township for ELISA analysis of serum anti-metacestode antibody. In 2018, no less than 30 sets of slaughtered yak organs including liver, lungs were randomly collected in each county, and tissue samples with lesions of hydatid cysts, masses or nodules were collected to be used for PCR amplification of mitochondrial cytochrome c oxidase subunit 1 (cox1) of Echinococcus spp. The yaks with positive PCR results were considered to have hydatid disease. Questionnaire was conducted to survey the awareness rate of echinococcosis knowledge in students, 50 students aged 6-12 years were randomly selected from each township every year. The survey data in 2016—2019 were analyzed including the positive rate in residents, the positive rate of Echinococcus coproantigen in domestic dogs, the positive rate of serum antibody or prevalence in cattle, and the changes of awareness rate of echinococcosis knowledge among students aged 6-12 years. Results From 2016 to 2019, the detection rates of new echinococcosis cases in the residents were 1.58‰ (693/439 091), 0.44‰ (204/460 165), 0.56‰ (244/436 473) and 0.18‰ (51/285 747), respectively, showing a trend of decrease (χ ² = 617.21, P < 0.05). The detection rates in children aged 6-12 years were 0.35‰ (693/439 091), 0.44‰ (204/460 165), 0.56‰ (244/436 473) and 0.18‰ (51/285 747), respectively, showing a trend of decrease (χ ² = 19.38, P < 0.05). The positive rate of Echinococcus coproantigen in domestic dogs were 16.50% (1241/7 519), 7.75% (501/6 464), 3.58% (63/1 758) and 3.32% (193/5 813), respectively, showing a trend of decrease (χ ² = 797.96, P < 0.05). The positive rates of serum antibody or prevalence in cattle were 10.27% (572/5 569), 10.05%(511/5 087), 4.07% (20/492), and 5.22% (141/2 700) in 2016, 2017, 2019, respectively, showing a trend of decrease (χ ² = 79.58, P < 0.05). In 2018, 492 sets of slaughtered yak organs were inspected,, of which 20 were positive, and the prevalence in cattle was 4.07%. The eligibility rates of the disease knowledge among students aged 6-12 were 89.20% (15 925/17 854), 93.90% (17 740/18 892), 94.92% (18 685/19 686), and 96.05% (23 564/24 532), showing an trend of increase (χ ² = 902.34, P < 0.05). Conclusion There have been great achievements by comprehensive control of echinococcosis in Ganzi Prefecture. The positive rate in redidents, the positive rate of dog Echinococcus coproantigen and the positive rate of serum antibody in cattle all decreased year by year, while the awareness rate of echinococcosis knowledge among students aged 6-12 years revealed a trend of increase.

Key words: Echinococcosis, Comprehensive control, Evaluation of effects, Ganzi Prefecture, Sichuan Province

CLC Number:

R532.32

KANG Dian-ju, ZHANG Jun-jie, SILANG Gema, DANBA Zeli, LIAO Sha, LIAO Ru-jun, ZHANG Meng-yuan, ZHONG Bo. Evaluation of the comprehensive control effects on echinococcosis in Ganzi Prefecture,Sichuan Province from 2016 to 2019[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(2): 150-155.

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年份 Year	人群 Residents				6~12岁儿童 Children aged 6-12 years
	检查人数 No. examined	检出患者数 No. patients	检出率/‰ Detection rate/‰		检查数 No. examined	检出患病儿童数 No. patients	检出率/‰ Detection rate/‰
	检查人数 No. examined	检出患者数 No. patients	检出率/‰ Detection rate/‰	2016	检查数 No. examined	检出患病儿童数 No. patients	检出率/‰ Detection rate/‰	439 091	693	1.58	68 166	24	0.35
2017	460 165	204	0.44		68 104	7	0.10
2018	436 473	244	0.56		70 096	10	0.14
2019	285 747	51	0.18		69 151	4	0.06
合计Total	1 023 100	1 192	1.17		275 517	45	0.16