Abstract: From June to December in 2008，five villages were randomly chosen from Pengjiang District of Jiangmen city and about five hundred residents from each village were examined for clonorchiasis by Kato-Katz method(three slides per specimen). Fifty residents from each village were re-examined one month after treatment. One year later 50 treated residents were chosen from Dalin village and Sanya village for fecal examination. Questionnairing was conducted to determine the knowledge rate on clonorchiasis prevention among residents. The percentage and usage of sanitary toilets were investigated. The average infection rate of clonorchiasis from five villages was 21.5%(537/2501). 86.6%(465/537)of clonorchiasis received treatment voluntarily. One month after treatment the infection rate in four villages declined significantly. The positive rate showed no significant difference between one month and one year after treatment in Dalin and Sanya villages(P>0.05). Questionairing indicated that 41.2%(170/413)of the clonorchiasis cases ate raw fish frequently, which was significantly higher than those non-infected people[4.2%，8/192]（P<0.05）. After health education, the knowledge awareness rate raised from 23.1%(135/584)to 84.5%(349/413)(P<0.05). The dissemination and usage of sanitary toilets were 93.2%(38 068/40 848)and 100%, respectively.

Key words: Clonorchis sinensis, Epidemiology, Control