Abstract: This review focused on the research progress in genetic features of Oncomelania hupensis， including its relation to the snail distribution, susceptibility to Schisotsoma japonicum. Series studies were done on genetic characteristics for snail distribution and its infectivity with S. japonicum by using population genetics and molecular biology approaches to explore the new avenue to block the transmission of schistosomiasis. However， limited progress has been achieved in this field inside in China comparing with global achievements. It is therefore recommended that future studies have to be focused on genetic features related to schistosome infections by referencing the study model of Biomphalaria glabrata / S. mansoni， and with assistance of modern technology on biomics， in order to improve investigations on genetics of Oncomelania hupensis in the country.

Key words: Oncomelania hupensis, Genetics, Biological Characteristics, Advances