›› 2008, Vol. 26 ›› Issue (4): 2-252.

• 论著 • Previous Articles     Next Articles

Epidemiology and Risk Factor Analysis for CanineEchinococcosis in a Tibetan Pastoral Area of Sichuan

HUANG Yan1*,Heath D David2,YANG Wen1,QIU Jia-min1,CHEN Xing-wang1,
YANG Yun1,WANG Qian1,LI Tiao-ying1,XIAO Yong-fu1,QIU Dong-chuan1,
XIAO Ning1,CHEN Fa-xi,GE Sang3,SE Duo4   

  1. 1 Sichuan Provincial Center for Disease Control and Prevention，Chengdu 610041，China；２ AgResearch，Wallaceville Animal Research Centre，PO Box 40063，Upper Hutt，New Zealand；３ Department of Agriculture and Animal Husbandry of Ganzi Tibetan Ethnic Autonomous County，Ganzi 626700，China；4 Center for Disease Control and Prevention of Ganzi Tibetan Ethnic Autonomous County，Ganzi 626700，China； 5 Xinjiang Provincial Center for Animal Disease Control and Diagnosis, Urumqi 830063，China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-08-30 Published:2008-08-30

PDF (PC)

Abstract: Objective To determine the prevalence and evaluate the risk factors of canine echinococcosis based on a field survey of dog infections with Echinococcus granulosus and E. multilocularis in Chalong, Kalong，Dade and Chazha Townships in a district of Ganzi County，Sichuan Province，China. Method Questionnairing associated with the acquisition of canine echinococcosis was administered to dog owners. Stray dogs were examined post-mortem and rectal faeces at necropsy were collected to validate a coproantigen ELISA. Owned dogs were screened for Echinococcus spp. infection in faeces using the genus specific copro-ELISA and the effectiveness of dog treatment was assessed. Chi-square and one-way ANOVA were used for statistical analysis. Results The prevalence of Echinococcus spp. infection at necropsy in stray dogs was 60.9% （14/23） in 2000； E. multilocularis infection accounted for 34.8% （8/23） and E. granulosus for 26.1% （6/23）. The specificity of the copro-ELISA was 80.0% and the sensitivity was 92.3%，compared with the results at necropsy. Fifty percent of owned dogs （290/580） tested was coproantigen positive at the beginning of the project in 2000, which decreased to 17%（99/580） in the same cohort of owned dogs after praziquantel treatment（5 mg/kg） at 6-monthly period from 2003 to 2005. Analysis for risk factors associated with coproantigen positive dogs showed that the never tethered dogs had a higher rate（40.4%，65/161） than dogs tethered during the day（32.3%，109/337）, or tethered at night [29.2%（21/72）], or those always tethered [20%（2/10）]（P＜0.01）. Dogs that their owners lacked hydatid transmission knowledge[38.1%（121/318）]and did not have de-worming practice[47.7%（92/193）]had significantly higher copro-antigen positive rate than those dogs that their owners knew relevant knowledge[28.6%（75/262）]and were dewormed regularly[20.4%(79/387）]（P＜0.05 and P＜0.01）. There was no correlation between the prevalence and dog sex or age or the varieties of livestock that the owner raised. Conclusion Local dogs show high prevalence with both E. granulosus and E. multilocularis. The copro-ELISA can be used to detect infection of Echinococcus in dogs. Allowing dogs to roam，lack of the basic knowledge of hydatid disease transmission and no de-worming practice for dogs are significant factors for the transmission of canine echinococcosis.

Key words: Echinococcus, Epidemiology, Coproantigen, Risk factor, Control, Prevalence, China