Abstract: 　Objective] To study the changes in T-lymphocyte subsets CD4+:CD8+ of peripheral blood in 29 patients with present chyluria(PPC), 29 patients with chyluria history but without chyluria (PNPC) and 38 healthy controls. [Methods] The determination of CD3+, CD4+ and CD8+ was conducted using test reagents kits. [Results] The percentage of CD3+, CD4+ cell were signfcantly decreased in PPS group than in PNPC and healthy control group,the ratio of CD4+/CD8+ being under 1.0.The T-lymphocyte subsets (CD3+, CD4+, CD8+) and CD4+/CD8+ ratio of both PNPC and healthy control group were all within normal range. [Conclusion] The immune function of the patients with filarial chyluria was impaired in terms of the changes in T-lymphocyte subsets.

Key words: Filariasis, chyluria, T-lymphocyte subsets.