ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS

›› 1999, Vol. 17 ›› Issue (5): 16-310.

• 动物模型 • Previous Articles Next Articles

ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS

DENG Xinguo¹;GUO Xue ²;PANG Guangren¹;TIAN Xiaoli ¹

1 Henan Institute of Ophthalmology;Zhengzhou 450003 2 Henan Health and Epidemic Station;Zhengzhou 450003

Received:1900-01-01 Revised:1900-01-01 Online:1999-10-30 Published:1999-10-30

Abstract

Abstract: 　AIM: To establish an animal model of Acanthamoeba keratitis. METHODS:Six New Zealand white rabbits were each injected intrastromally with Acanthamoeba suspension 3 days after subconjunctival injection with dexamethasone. RESULTS:All of the 6 rabbits developed keratitis. Acanthamoeba protozoa were identified by the methods of corneal scraping with 10% potassium hydroxide wet mount examined under microscope,corneal protozoa culture and pathological section examination. CONCLUSION:A rabbit model of Acanthamoeba keratitis was established.

Key words: Acanthamoeba keratitis, animal model, intrastromal injection

DENGXinguo;GUOXue;PANGGuangren;TIANXiaoli. ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS[J]. , 1999, 17(5): 16-310.

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ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS

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