Abstract: From 1987 to 1989, a survey was made on 51 883 residents in 100 sites of 20 counties and cities of Guangxi Zhuang Autonomous Region. The investigated sites, located respectively in north,south, west, east and central Guangxi, were selected according to different topography and socioeconomic status by stratified cluster sampling. The overall parasitic infection rate was 85.3%. A total of 24 species of parasites were found, including 7 species of nematodes, 2 species of trematodes, 4 species of cestodes and 11 species of protozoa. The most commonly infected parasites were Ascaris lumbricoides, Trichuris trichiura, hookworm and Enterobius vermicularis . Their infection rates were 66.0%, 47.7%, 37.8% and 35.5%,respectively. It is suggested that infections of these four parasites should be listed as major ones in control program of Guangxi. Multiparasitism was very common, 68.5% of the infected persons haboured two or more than two species of parasites. The highest record falls on a person who was infected with 8 species of parasites. The infection rate of children of 5-14 year age group was 89.9%, being the highest among different age groups. The infection rate in females was significantly higher than in males. In the counties with poor cultural , hygienic and economic conditions, the infection rates were generally higher than the well off counties. A suggestion is made that the control practice should be focused on children, women and people living in the underdeveloped areas.