Application of mitochondrial genes in the molecular taxonomic identification and phylogenetic analysis of Taeniidae

doi:10.12140/j.issn.1000-7423.2022.06.012

Abstract

Abstract:

Echinococcosis or cysticercosis caused by the Taeniidae species is a zoonotic parasitic disease that has a significant impact on the social economy and public health. Accurate identification of the relevant species is helpful for the prevention, control, and even eliminate of the diseases. Currently, mitochondrial genes used in molecular classification and phylogenetic studies of Taeniidae are mainly cytochrome C oxidase subunit 1 gene, cytochrome B gene, and NADH dehydrogenase subunit 1 gene. This paper reviews the current advances of molecular classification and phylogenetic analysis of the Taenia and Echinococcus in the family Taeniidae, mainly from the perspective of mitochondrial genes.

Key words: Taeniidae, Mitochondrial gene, Molecular taxonomic identification, Phylogeny

CLC Number:

R383.2

CHEN Qi-lu, WANG Xu, LI Chun-yang, GUAN Ya-yi. Application of mitochondrial genes in the molecular taxonomic identification and phylogenetic analysis of Taeniidae[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(6): 767-773.

Figures/Tables 1

References 60

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基因	优缺点	参考文献
cox1	较其他线粒体基因具有更有效的遗传信息，基因保守，适用于种间及种以上的分类鉴别和系统进化研究	[6,11⇓⇓-14]
cytb	进化速率适中，较短片段即包含种、属、纲水平的系统发育信息，序列相对稳定且高度保守，但种间的序列差异非常大，可作为牛带绦虫和亚洲带绦虫分类研究的分子标志	[24,57]
nad1	结构简单、进化速率快，较cox1基因更加适合作为研究绦虫系统进化的分子标志	[9,34⇓⇓-37]
其他线粒体基因	12S rRNA的高变异区位于保守延伸区内，多用于近缘种研究。nad5在带绦虫属中差异程度最大，在棘球绦虫属中变异率最大	[6,9,24,55]