Research progress on tick protective antigens

doi:10.12140/j.issn.1000-7423.2021.04.020

Abstract

Abstract:

Ticks are obligate hematophagous ectoparasites that can transmit a variety of pathogens, having harmful impacts on human health and the husbandry industry. Screening for efficient protective antigens to develop anti-tick vaccines has become a safe and effective strategy for tick control. This paper briefly introduces the commercial Bm86 protective antigen, and summarizes current status of protective antigens with different characteristics derived from tick salivary glands, midgut, gonads and eggs, as well as protective antigens of enzymes, protease inhibitors and conservative proteins. The review will provide a scientific basis for the development of anti-tick vaccines.

Key words: Tick, Protective antigen, Anti-tick vaccine

CLC Number:

R384.41

LV Li-hong, ZHANG Jin-cheng, HU Yong-hong. Research progress on tick protective antigens[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(4): 542-547.

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