Advances in research on the roles of natural killer T cells in immune responses to parasitic infections

doi:10.12140/j.issn.1000-7423.2020.04.014

Abstract

Abstract:

Natural killer T(NKT) cells are a type of innate immune cells that express both T cell and NK cell surface markers. The cytokines secreted by NKT cells upon activation possess some properties that affect the adaptive immunity, thus bridging innate and adaptive immunity and playing important roles in anti-infection processes, tumor immunity and autoimmune diseases. NKT cells also play an important role in bridging innate and adaptive immunity during immune responses to parasitic infections. However, little research has been conducted in this field. In this article, the roles of NKT cells in immune responses to Leishmania, Plasmodium, Trypanosoma and Schistosoma infections are reviewed.

Key words: Parasite infection, Natural killer T cells, Immunity

CLC Number:

LIU Yi, CAI Yu-chun, CHEN Shao-hong, CHEN Jia-xu. Advances in research on the roles of natural killer T cells in immune responses to parasitic infections[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(4): 477-481.

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