胞外囊泡在寄生蠕虫中的研究进展

摘要/Abstract

摘要：

胞外囊泡是由多种细胞分泌的囊状小体,内含大量的蛋白质、脂类和核酸等生物活性物质,广泛参与细胞间物质交换和信息传递。已有研究表明,寄生虫可利用胞外囊泡进行细胞间通讯,并通过胞外囊泡将一系列生物活性分子转移到宿主细胞,调节宿主免疫系统。本文对胞外囊泡在寄生蠕虫中的研究进展作一综述,为其在寄生虫领域的研究提供新的思路。

关键词: 胞外囊泡, 蠕虫, 宿主, 互作机制

Abstract:

Extracellular vesicles are vesicular bodies secreted by a variety of cells and contain large amounts of biologically active substances such as proteins, lipids and nucleic acids. They are widely involved in intercellular substance exchange and information transmission. Studies have shown that parasites can conduct intercellular communications and transfer a series of biologically active molecules to host cells through extracellular vesicles to regulate the host immune system. This review summarizes the research progress on extracellular vesicles in parasitic helminthes, in order to provide new ideas for the study of extracellular vesicles in the field of parasites.

Key words: Extracellular vesicle, Helminth, Host, Interaction mechanism

中图分类号:

R383

张小凡, 巩文词, 沈玉娟. 胞外囊泡在寄生蠕虫中的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(6): 648-654.

Xiao-fan ZHANG, Wen-ci GONG, Yu-juan SHEN. Research progress on extracellular vesicles of helminthes[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2018, 36(6): 648-654.

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