隐孢子虫和蓝氏贾第鞭毛虫分子流行病学研究进展

中国寄生虫学与寄生虫病杂志 ›› 2018, Vol. 36 ›› Issue (6): 661-666.

隐孢子虫和蓝氏贾第鞭毛虫分子流行病学研究进展

徐宁, 尹建海, 沈玉娟, 刘华, 曹建平^*()

中国疾病预防控制中心寄生虫病预防控制所,国家热带病研究中心,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织热带病合作中心,科技部国家级热带病国际联合研究中心,上海 200025

收稿日期:2018-07-05 出版日期:2018-12-30 发布日期:2019-01-08
通讯作者: 曹建平
基金资助:
国家公益性卫生行业科研专项（No. 201502021）;国家科技重大专项（No. 2018ZX10713001-004, No. 2018ZX10201002-009-004）;国家重点研发计划（No. 2016YFC1201900）

Advances in molecular epidemiology of Cryptosporidium and Giardia lamblia

Ning XU, Jian-hai YIN, Yu-juan SHEN, Hua LIU, Jian-ping CAO^*()

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory of Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China

Received:2018-07-05 Online:2018-12-30 Published:2019-01-08
Contact: Jian-ping CAO
Supported by:
Supported by the National Special Program for Scientific Research of Public Health of China (No. 201502021), the National Science and Technology Major Program of China (No. 2018ZX10713001-004 and 2018ZX10201002-009-004) and the Special National Project on Research and Development of Key Biosafety Technologies of China (No. 2016YFC1201900)

摘要/Abstract

摘要：

宿主被隐孢子虫和蓝氏贾第鞭毛虫（简称贾第虫）感染后会出现腹泻等健康问题,严重时可致死亡。隐孢子虫病和贾第虫病均属于新发传染病,其疾病负担往往被低估,是被忽视的重要公共卫生问题。分子生物学技术在隐孢子虫和贾第虫的检测、基因分型及溯源等方面发挥着重要作用。本文就隐孢子虫和贾第虫的分子流行病学进展作一综述,为其防控提供依据。

关键词: 隐孢子虫, 蓝氏贾第鞭毛虫, 基因分型, 分子流行病学, 腹泻

Abstract:

The infections of Cryptosporidium and Giardia lamblia cause diarrhea mainly and even death in severe cases. Cryptosporidiosis and giardiasis are emerging infectious diseases and the important public health problems that have been neglected and the disease burden is often underestimated. Recently developed molecular biology techniques have played important roles in the detection, genotyping and traceability of these parasitic protozoans. In this paper, the molecular epidemiology of Cryptosporidium and Giardia lamblia is reviewed in order to provide information for the better prevention and control of these infections.

Key words: Cryptosporidium, Giardia lamblia, Genotyping, Molecular epidemiology, Diarrhea

中图分类号:

徐宁, 尹建海, 沈玉娟, 刘华, 曹建平. 隐孢子虫和蓝氏贾第鞭毛虫分子流行病学研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(6): 661-666.

Ning XU, Jian-hai YIN, Yu-juan SHEN, Hua LIU, Jian-ping CAO. Advances in molecular epidemiology of Cryptosporidium and Giardia lamblia[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2018, 36(6): 661-666.

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