中国寄生虫学与寄生虫病杂志

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青海省玉树藏族自治州学生棘球蚴病流行情况调查分析

程时磊,马霄*,蔡辉霞,刘娜,刘玉芳,史可梅   

  1. 青海省地方病预防控制所,西宁 811602
  • 出版日期:2018-06-30 发布日期:2018-07-02

Epidemiological investigation of hydatid disease prevalence among students in Yushu Prefecture of Qinghai Province

CHENG Shi-lei, MA Xiao*, CAI Hui-xia, LIU Na, LIU Yu-fang, SHI Ke-mei   

  1. Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602
  • Online:2018-06-30 Published:2018-07-02

摘要:

为了解青海省玉树州学生棘球蚴病的流行情况,于2012年6-8月随机抽取玉树州称多县、囊谦县、曲麻莱县、玉树县、杂多县和治多县等6县16乡(镇)的22所学校,对7~15周岁学生进行腹部B超和血清ELISA检测。结果显示,B超检查7 454人,检出棘球蚴病患者58例,棘球蚴病检出率为0.78%。ELISA检测7 081人,检出棘球蚴血清抗体阳性302例,抗体阳性率为4.26%。男性和女性B超棘球蚴病检出率均为0.78%(30/3 853、28/3 601);女性血清抗体阳性率为4.62%(158/3 423),男性为3.94%(144/3 658)(P > 0.05)。不同地区中,称多县B超检出率最高,为1.67%(27/1 612)(χ2 = 35.224,P < 0.05);曲麻莱县血清抗体阳性率最高,为6.68%(82/1 228)(χ2 = 32.817,P < 0.05)。不同年龄组中,14~岁人群B超棘球蚴病检出率和血清抗体阳性率均最高,分别为1.50%(10/666)和7.20%(46/639)(χ2 = 13.451、53.284,P < 0.05)。提示青海省玉树州学生棘球蚴病检出率和血清抗体阳性率较高,需加强对学生人群的棘球蚴病监测和宣传教育。

关键词: 棘球蚴病, 学生, 流行, 调查, 青海, 玉树

Abstract:

To understand the prevalence of hydatid disease among students in Yushu Prefecture, 22 schools were randomly selected from 16 towns in 6 counties including Chengduo County, Nangqian County, Qumalai County, Yushu County, Zaduo County and Zhiduo County from June to August, 2012. Students aged 7-15 were examined by B-ultrasound and serum ELISA. A total of 7 454 students were examined by B-ultrasound, of whom 58 were detected with hydatid cysts, with a prevalence of 0.78%. A total of 7 081 students were examined by ELISA, of whom 302 were detected to be positive for anti-Echinococcus antibody, with a positive rate of 4.26%. The detection rates by B ultrasound in males and females were both 0.78% (30/3 853, 28/3 601). The antibody positive rate in females was 4.62% (158/3 423), and 3.94% in males (144/3 658) (P > 0.05). Among different regions, the Chengduo County had the highest B ultrasound detection rate (1.67%, 27/1 612) (χ2 = 35.224, P < 0.05), while Qumalai had the highest positive rate of anti-Echinococcus (6.68%, 82/1 228) (χ2 = 32.817, P < 0.05). Among the different age groups, the group of >14 years ranked top with regard to the detection rate by B ultrasound (1.50%, 10/666)(χ2 = 13.451, P < 0.05) and the positive rate of anti-Echinococcus (7.20%, 46/639) (χ2 = 53.284, P < 0.05). The results suggested a high prevalence and a high positive rate of anti-Echinococcus among students in Yushu Prefecture of Qinghai Province. Efforts should be made to strengthen the education and surveillance of hydatid disease among students.
  

Key words: Hydatid disease, Student, Epidemiology, Investigation, Qinghai, Yushu