中国寄生虫学与寄生虫病杂志 ›› 2007, Vol. 25 ›› Issue (2): 17-157.

• 综述 • 上一篇    下一篇

弓形虫侵入宿主细胞的研究进展

李学瑞1;王艳华1;赵象忠2;张德林1   

  1. 1中国农业科学院兰州兽医研究所 家畜疫病病原生物学国家重点实验室 甘肃省动物寄生虫病重点实验室, 兰州 730046; 2甘肃畜牧工程职业技术学院, 武威 733006
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-04-30 发布日期:2007-04-30
  • 通讯作者: 张德林

Update on Host Cell Invasion by Toxoplasma gondii

LI Xue-rui1;WANG Yan-hua1;ZHAO Xiang-zhong2;ZHANG De-lin1   

  1. 1 Lanzhou Veterinary Research Institute, Chinese Acedemy of Agricultural Sciences, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou 730046, China; 2 Gansu College of Husbandry Engineering, Huangyangzheng 733006, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-30 Published:2007-04-30
  • Contact: ZHANG De-lin

摘要: 在弓形虫侵入宿主细胞的过程中,弓形虫表面抗原(surface antigen,SAG)、微线体蛋白(micronemes,MIC)、棒状体蛋白(rhoptry protein,ROP)、致密颗粒抗原(dense granules antigen,GRA)及钙离子起着重要的作用,蛋白激酶则对弓形虫侵入宿主细胞过程所必需的蛋白质的正确折叠及加工起作用。本文对此进行了简单综述。

关键词: 弓形虫, 侵入机理, 宿主细胞

Abstract: This paper reviewed the importance of micronemes, dense granules, rhoptry and major surface proteins of Toxoplasma gondii, and of calcium during the host cell invasion as well as the role of T. gondii proteases in the folding and processing of these proteins.

Key words: Toxoplasma gondii, Invasion mechanism, Host cell