中国寄生虫学与寄生虫病杂志 ›› 1997, Vol. 15 ›› Issue (6): 403-404.

• 防治经验 • 上一篇    下一篇

试条法快速诊断恶性疟的研究

杜建伟; 胡玉銮; 蔡祖芳; 蒙锋   

  1. 海南省热带病防治研究所
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1997-12-28 发布日期:1997-12-28

RAPID DIAGNOSISOF FALCIPARUM MALARIA BY DIPSTICK METHOD

Du Jianwei; Hu Yuluan; Cai Zufang; Meng Feng   

  1. Hainan Provincial Institute of Tropical Diseases; Haikou 570203
  • Received:1900-01-01 Revised:1900-01-01 Online:1997-12-28 Published:1997-12-28

摘要: 目的 :探讨试条法检测恶性疟患者血液中富组氨酸蛋白 快速诊断恶性疟在海南疟区现场的诊断价值。方法 :用试条法检测 66例发热病人血样 ,将结果同血涂片镜检法进行比较。结果 :试条法检出恶性疟 (包括混合感染 )的敏感度和特异度分别为 85.7%和95.6% ,两种检测法的符合率为 92 .4 % ;用试条法检测 2 0例间日疟患者血样无交叉反应。结论 :试条法诊断恶性疟快速方便 ,能诊断早期恶性疟患者。

关键词: 恶性疟, 富组蛋白, 试条法, 诊断

Abstract: AIM:To explore the practical value of dipstick method for the diagnosis of falciparum malaria by detecting histidine-rich protein in blood
with a dipstick. METHOD:Blood samples collected from 66 febrile cases in
outpatient department in malaria endemic areas in Hainan Province were detected
by dipstick method and microscopy. The examination results of the two methods
were compared. RESULTS:The sensitivity and specificity of dipstick method were 85.7% and 95.6%, and the positive and negative predictive values were 90.0%
and 93.5% respectively; The coincidence rate with microscopy was 92.4%. None of the 20 samples of vivax malaria showed cross reaction. CONCLUSION: It is a very convienent and rapid diagnostic method for early treatment and effective prevention of falciparum malaria in malaria endemic areas.

Key words: Plasmodium falciparum, histidine- rich protein 2, dipstick, diagnosi