关键词: 间日疟原虫, 实验观察, 长潜伏期, 短潜伏期, 志愿者, 广西, 生物学特性, 感染源, 寄生虫学, 潜隐期

Abstract: 39 healthy volunteers were experimentally inoculated with Plasmodium vivax from Guangxi by mosquito bite, and 32 of them were successfully infected. 25 of the infected volunteers (78.1%) had a short incubation period (mean: 16.4 days) prior to the onset of malaria attack, while seven individuals had long-term incubation period of 238 to 314 days (mean: 274.7±29.3 days). Relapses occurred in all cases with short-term incubation period after a long latency without exception; most of them had l to 2 relapses, some, 3 relapses. Among the seven cases with long incubation period, only one relapse occurred in five, and the remaining two had no relapse at all. It was shown that although Guangxi was situated in subtropical zone, Plasmodium vivax there was characteristie of the temperate zone type. A comparison of Plasmodium vivax from Guangxi with those from south Yunnan and Henan suggested that they differ in the composition of sporozoite subpopulations classified arbitrarily according to the duration of development of bradysporozoites in hepatic cells.