中国寄生虫学与寄生虫病杂志 ›› 2026, Vol. 44 ›› Issue (4): 461-467.doi: 10.12140/j.issn.1000-7423.2026.04.001

• 特约综述 • 上一篇    下一篇

近20年我国广州管圆线虫病流行与控制

何安琪1()(), 田霞2, 吕山1,*()()   

  1. 1 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心), 传染病溯源预警与智能决策全国重点实验室,国家卫生健康委员会寄生虫病原与媒介生物学重点实验室,世界卫生组织热带病合作中心,科技部国家级热带病国际联合研究中心, 上海 200025
    2 徐汇区疾病预防控制中心, 上海 200237
  • 收稿日期:2026-02-02 修回日期:2026-04-03 出版日期:2026-08-30 发布日期:2026-08-19
  • 通讯作者: * 吕山(ORCID:0000-0003-2086-807X),男,博士,研究员,从事寄生虫病防治与全球卫生研究。E-mail:lvshan@nipd.chinacdc.cn
  • 作者简介:何安琪(ORCID:0009-0004-1599-5941),女,硕士研究生,从事全球卫生研究。E-mail:heanqi0371@163.com
    作者贡献

    何安琪负责文献资料收集和论文撰写,田霞负责文献资料收集,吕山负责审校、修订。

  • 基金资助:
    新发突发与重大传染病防控国家科技重大专项(2025ZD01900304)

Epidemiology and control of angiostrongyliasis in China during the recent 20 years

HE Anqi1()(), TIAN Xia2, LV Shan1,*()()   

  1. 1 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China
    2 Xuhui District Center for Disease Control and Prevention, Shanghai 200237, China
  • Received:2026-02-02 Revised:2026-04-03 Online:2026-08-30 Published:2026-08-19
  • Contact: * E-mail: lvshan@nipd.chinacdc.cn
  • Supported by:
    Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project(2025ZD01900304)

摘要:

2006年北京广州管圆线虫病暴发后,我国围绕该病开展了流行病学调查、监测预警、诊断治疗及相关研究。近20年来,北京、广东广宁、云南大理等地先后报告聚集性疫情,病例报告总体下降,但部分地区仍持续发现病例;福寿螺等中间宿主持续扩散,自然疫源地范围扩大,传播风险仍然存在。我国已逐步建立病例、宿主和风险预警相结合的防控体系,并不断完善诊断标准、专家共识和分子检测技术。本文综述近20年我国广州管圆线虫病的流行变化、监测响应、诊断治疗及科研进展,为进一步完善防控策略提供参考。

关键词: 广州管圆线虫, 流行病学, 监测预警, 诊断与治疗, 防控策略

Abstract:

Since the outbreak of angiostrongyliasis in Beijing in 2006, epidemiological investigations, surveillance and early warning, diagnosis and treatment, and other related studies had been conducted targeting this disease in China. During the past two decades, cluster outbreaks had been successively reported in Beijing Municipality, Guangning County of Guangdong Province, and Dali City of Yunnan Province. Although the overall number of reported angiostrongyliasis cases has declined during the past 20 years, cases continue to be detected in selected areas. In addition, intermediate hosts, such as Pomacea snails, have continued to spread, and the coverage of natural foci has expanded, indicating that angiostrongyliasis transmission risk remains. An angiostrongyliasis control system has been gradually built in China, which combines case surveillance, host surveillance, and risk early warning, and diagnostic criteria, expert consensus, and molecular diagnostic assays have been continuously improved. This article summarizes the epidemiological changes, surveillance and response, diagnosis and treatment, and research advances of angiostrongyliasis in China over the past 20 years, which provide insights into improvements in the disease control strategies.

Key words: Angiostrongylus cantonensis, Epidemiology, Surveillance and early warning, Diagnosis and treatment, Control strategies

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