新发传染病全球大流行的挑战与跨部门综合防控策略

doi:10.12140/j.issn.1000-7423.2024.03.001

中国寄生虫学与寄生虫病杂志 ›› 2024, Vol. 42 ›› Issue (3): 279-285.doi: 10.12140/j.issn.1000-7423.2024.03.001

新发传染病全球大流行的挑战与跨部门综合防控策略

谷思雨¹^,²(), 强讷¹^,², 李天韵¹^,², 韩乐飞¹^,², 周晓农¹^,²^,³^,^*()

1 上海交通大学医学院-国家热带病研究中心全球健康学院，上海 200025
2 上海交通大学-爱丁堡大学全健康研究中心，上海 200025
3 中国疾病预防控制中心寄生虫病预防控制所（国家热带病研究中心），传染病溯源预警与智能决策全国重点实验室，国家卫生健康委员会寄生虫病原与媒介生物学重点实验室，世界卫生组织热带病合作中心，科技部国家级热带病国际研究中心，上海 200025

收稿日期:2024-04-04 修回日期:2024-05-06 出版日期:2024-06-30 发布日期:2024-07-16
通讯作者: *周晓农（1962—），男，博士，研究员，从事医学寄生虫学研究。E-mail：zhouxn1@chinacdc.cn
作者简介:谷思雨（1997—），女，硕士研究生，从事全球传染病流行病学研究。E-mail：Gusiyu_cd@163.com
基金资助:
上海市“科技创新行动计划”“一带一路”国际合作项目热带病防治澜湄联合实验室(21410750200);上海市“科技创新行动计划”启明星培育（扬帆专项）(23YF1421200)

Challenges of the global pandemics of emerging infectious diseases and integrated intersectoral prevention strategy

GU Siyu¹^,²(), QIANG Ne¹^,², LI Tianyun¹^,², HAN Lefei¹^,², ZHOU Xiaonong¹^,²^,³^,^*()

1 School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
2 One Health Center, Shanghai Jiao Tong University-the University of Edinburgh, Shanghai 200025, China
3 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China

Received:2024-04-04 Revised:2024-05-06 Online:2024-06-30 Published:2024-07-16
Supported by:
International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion of Shanghai Science and Technology Innovation Action Plan(21410750200);Shanghai Science and Technology Development Foundation(23YF1421200)

摘要/Abstract

摘要：

新发传染病（EID）是指新出现的或既往已经存在但发病率或影响范围迅速增加的传染性疾病。受气候变化、病原体进化等因素影响，EID发生频率及形成大流行的风险在不断增加。新型冠状病毒感染等疾病的暴发已经对全球健康、经济和社会稳定造成了巨大冲击。这些疾病的全球大流行不仅直接影响人类健康，还给经济发展、贫困减少和教育等方面带来诸多负面影响。为了有效应对EID的挑战，国家和国际组织采取了一系列综合性防控策略，包括降低病原体溢出风险、建立综合性监测与预警系统、协调部门间的合作与信息共享以及以全健康（One Health）理念开展跨部门联防联控。当下EID防控依然面临诸多挑战，本文总结EID大流行所带来的挑战、国家及国际层面的应对防控策略以及当前防控的进展和具体案例，为将来应对EID大流行提供经验参考。

关键词: 新发传染病, 全球大流行, 防控策略, 全健康

Abstract:

Emerging infectious diseases (EIDs) are either newly emerging or previously existing infectious diseases that are experiencing a rapid increase in incidence or geographic spread. The risk of EIDs outbreaks and pandemics is escalating due to factors such as climate change, pathogen evolution. Outbreaks of EIDs, like coronavirus disease 2019 (COVID-19), have significantly impacted on global health, the economy, and social stability. Such global pandemics not only directly affect human health but also negatively impact on economic development, poverty reduction, and education. To tackle the challenges of EIDs, organizations at national and international levels have adopted a series of comprehensive prevention and control strategies, including reducing the risk of pathogen spillover, establishing comprehensive detection and early warning systems, and promoting cross-sectoral collaboration and sharing information with other departments, and implementing the One Health concept for cross-sectoral prevention and control. This article summarizes the challenges posed by EIDs pandemics, the prevention and control strategies at the national and international levels, the current progress, and specific cases to provide a reference for future responses to EIDs pandemics.

Key words: Emerging infectious diseases, Pandemic, Intersectoral integrated control strategy, One Health

中图分类号:

谷思雨, 强讷, 李天韵, 韩乐飞, 周晓农. 新发传染病全球大流行的挑战与跨部门综合防控策略[J]. 中国寄生虫学与寄生虫病杂志, 2024, 42(3): 279-285.

GU Siyu, QIANG Ne, LI Tianyun, HAN Lefei, ZHOU Xiaonong. Challenges of the global pandemics of emerging infectious diseases and integrated intersectoral prevention strategy[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2024, 42(3): 279-285.

图/表 2

参考文献 46

[1]	Jones KE, Patel NG, Levy MA, et al. Global trends in emerging infectious diseases[J]. Nature, 2008, 451(7181): 990-993.
[2]	Gubler DJ. The global threat of emergent/Re-emergent vector-borne diseases[M]// Vector biology, ecology and control. Dordrecht: Springer, 2010: 39-62.
[3]	Grace D, Mutua FK, Ochungo P, et al. Mapping of poverty and likely zoonoses hotspots[EB/OL]. (2012-07-02)[2024-03-20]. https://cgspace.cgiar.org/items/c879acdd-6b11-4166-aa8d-48049783b453.
[4]	Chmielewski R, Swayne DE. Avian influenza: public health and food safety concerns[J]. Annu Rev Food Sci Technol, 2011, 2: 37-57.
[5]	Taubenberger JK, Morens DM. 1918 influenza: the mother of all pandemics[J]. Emerg Infect Dis, 2006, 12(1): 15-22.
[6]	Our World in Data. Coronavirus pandemic (COVID-19) [EB/OL]. (2020-01-01)[2024-01-23]. https://ourworldindata.org/coronavirus.
[7]	Jacob ST, Crozier I, Fischer WA, et al. Ebola virus disease[J]. Nat Rev Dis Primers, 2020, 6: 13. doi: 10.1038/s41572-020-0147-3 pmid: 32080199
[8]	U.S. Department of Health & Human Services. History of Ebola outbreaks[EB/OL]. (2023-08-30)[2024-04-01]. https://www.cdc.gov/vhf/ebola/history/chronology.html
[9]	de Wit E, van Doremalen N, Falzarano D, et al. SARS and MERS: recent insights into emerging coronaviruses[J]. Nat Rev Microbiol, 2016, 14(8): 523-534. doi: 10.1038/nrmicro.2016.81 pmid: 27344959
[10]	Li YT, Linster M, Mendenhall IH, et al. Avian influenza viruses in humans: lessons from past outbreaks[J]. Br Med Bull, 2019, 132(1): 81-95.
[11]	Plourde AR, Bloch EM. A literature review of Zika virus[J]. Emerg Infect Dis, 2016, 22(7): 1185-1192. doi: 10.3201/eid2207.151990 pmid: 27070380
[12]	Khetarpal N, Khanna I. Dengue fever: causes, complications, and vaccine strategies[J]. J Immunol Res, 2016, 2016: 6803098.
[13]	Crook H, Raza S, Nowell J, et al. Long covid-mechanisms, risk factors, and management[J]. BMJ, 2021, 374: n1648.
[14]	Davis HE, McCorkell L, Vogel JM, et al. Long COVID: major findings, mechanisms and recommendations[J]. Nat Rev Microbiol, 2023, 21(3): 133-146. doi: 10.1038/s41579-022-00846-2 pmid: 36639608
[15]	Collaborators C1 MD. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic[J]. Lancet, 2021, 398(10312): 1700-1712. doi: 10.1016/S0140-6736(21)02143-7 pmid: 34634250
[16]	World Health Organization. Second round of the national pulse survey on continuity of essential health services during the COVID-19 pandemic[EB/OL]. (2021-04-23)[2023-11-12]. https://www.who.int/publications/i/item/WHO-2019-nCoV-EHS-continuity-survey-2021.1.
[17]	Hanna TP, King WD, Thibodeau S, et al. Mortality due to cancer treatment delay: systematic review and meta-analysis[J]. BMJ, 2020, 371: m4087.
[18]	World Health Organization. Mental health and COVID-19: early evidence of the pandemic’s impact[EB/OL]. (2022-03-02)[2024-03-29]. https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci_Brief-Mental_health-2022.1.
[19]	World Health Organization. COVID-19 disrupting mental health services in most countries, who survey[EB/OL]. (2020-10-05)[2023-08-18]. https://www.who.int/news/item/05-10-2020-covid-19-disrupting-mental-health-services-in-most-countries-who-survey.
[20]	Chen RC, Haynes K, Du SM, et al. Association of cancer screening deficit in the United States with the COVID-19 pandemic[J]. JAMA Oncol, 2021, 7(6): 878-884. doi: 10.1001/jamaoncol.2021.0884 pmid: 33914015
[21]	United Nations Department of Economic and Social Affairs. Sustainable development outlook 2021: from anguish to determination[EB/OL]. (2021-09-20)[2023-11-12]. https://www.un.org/development/desa/dpad/publication/sustainable-development-outlook-2021-from-anguish-to-determination/.
[22]	Food and Agriculture Organization. The state of food security and nutrition in the world 2021[EB/OL]. (2021-09-20)[2023-12-23]. https://www.who.int/publications/m/item/the-state-of-food-security-and-nutrition-in-the-world-2021.
[23]	International Monetary Fund. World economic outlook recovery during a pandemic[EB/OL]. (2021-10-01)[2023-11-15]. https://www.imf.org/en/Publications/WEO/Issues/2021/10/12/world-economic-outlook-october-2021.
[24]	United Nations Development Programme. Long-term socio-economic impacts of COVID-19 in African contexts[EB/OL]. (2021-03-11)[2023-12-25]. https://www.undp.org/africa/publications/long-term-socio-economic-impacts-covid-19-african-contexts.
[25]	World Health Organization. Weekly epidemiological update on COVID-19 10-August 2022[EB/OL]. (2022-08-10)[2024-04-03]. https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---10-August-2022.
[26]	United Nations Statistics Division. The sustainable development goals report 2022[EB/OL]. (2022-07-07)[2024-03-30]. https://unstats.un.org/sdgs/report/2022/.
[27]	World Bank. Poverty and shared prosperity 2020: reversals of fortune[EB/OL]. (2022-10-07)[2024-03-09]. https://www.worldbank.org/en/publication/poverty-and-shared-prosperity.
[28]	Mahler NYCLDG. Is COVID-19 increasing global inequality?[EB/OL]. (2021-10-07)[2022-09-02]. https://blogs.worldbank.org/opendata/covid-19-increasing-global-inequality.
[29]	MacKenzie JS, Jeggo M, Daszak P, et al. One health: the human-animal-environment interfaces in emerging infectious diseases: the concept and examples of a one health approach[M/OL]. New York: Springer, 2013. (2013-11-22)[2024-04-02]. https://link.springer.com/book/10.1007/978-3-642-35846-3.
[30]	Presti AL, Cella E, Giovanetti M, et al. Origin and evolution of Nipah virus[J]. J Med Virol, 2016, 88(3): 380-388. doi: 10.1002/jmv.24345 pmid: 26252523
[31]	Robert Koch Institute. Rki 2025: Public health in times of digitalization and globalization[EB/OL]. (2017-06-26)[2024-03-20]. https://www.rki.de/EN/Content/Institute/RKI2025/RKI_2025_ strategy.html.
[32]	U.S. Center for disease control and prevention. National Electronic Disease Surveillance System Base System[EB/OL]. (2024-02-21)[2024-05-19]. https://www.cdc.gov/nbs/php/.
[33]	O’Sullivan JD, Allworth AM, Paterson DL, et al. Fatal encephalitis due to novel paramyxovirus transmitted from horses[J]. Lancet, 1997, 349(9045): 93-95. pmid: 8996421
[34]	Chua KB. Risk factors, prevention and communication strategy during Nipah virus outbreak in Malaysia[J]. Malays J Pathol, 2010, 32(2): 75-80. pmid: 21329177
[35]	World Health Organization. WHO launches global network to detect and prevent infectious disease threats[EB/OL]. (2023-05-20)[2024-03-19]. https://www.who.int/news/item/20-05-2023-who-launches-global-network-to-detect-and-prevent-infectious-disease-threats.
[36]	World Health Organization. Pandemic prevention, preparedness and response accord[EB/OL]. (2023-06-28)[2024-03-20]. https://www.who.int/news-room/questions-and-answers/item/pandemic-prevention--preparedness-and-response-accord.
[37]	World Bank. World bank approves US$30 million credit to strengthen disease surveillance in Sierra Leone[EB/OL]. (2016-06-29)[2024-03-21]. https://www.worldbank.org/en/news/press-release/2016/06/29/world-bank-approves-us30-million-credit-to-strengthen-disease-surveillance-in-sierra-leone.
[38]	Rabinowitz PM, Kock R, Kachani M, et al. Toward proof of concept of a one health approach to disease prediction and control[J]. Emerg Infect Dis, 2013, 19(12): e130265.
[39]	Li HM, Liu JS, Wang XH, et al. Integrated surveillance and early warning system for emerging infectious diseases based on One Health concept: structures and innovations[J]. Chin J Parasitol Parasit Dis, 2022, 40(5): 572-578. (in Chinese)
	(李慧敏, 刘婧姝, 王希涵, 等. 基于全健康理念的新发传染病综合监测预警体系: 结构与创新[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(5): 572-578.) doi: 10.12140/j.issn.1000-7423.2022.05.002
[40]	Liu JS, Zhang XX, Guo XK. The origin, connotation and prospect of One Health[J]. Chin J Parasitol Parasit Dis, 2022, 40(1): 1-11. (in Chinese)
	(刘婧姝, 张晓溪, 郭晓奎. 全健康的起源、内涵及展望[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(1): 1-11.). doi: 10.12140/j.issn.1000-7423.2022.01.001
[41]	Claas EC, Osterhaus AD, van Beek R, et al. Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus[J]. Lancet, 1998, 351(9101): 472-477. pmid: 9482438
[42]	Sims LD, Peiris M. One health: the Hong Kong experience with avian influenza[J]. Curr Top Microbiol Immunol, 2013, 365: 281-298. doi: 10.1007/82_2012_254 pmid: 22903569
[43]	Wong G, Kobinger GP. Backs against the wall: novel and existing strategies used during the 2014-2015 Ebola virus outbreak[J]. Clin Microbiol Rev, 2015, 28(3): 593-601. doi: 10.1128/CMR.00014-15 pmid: 25972518
[44]	Moll R, Reece S, Cosford P, et al. The Ebola epidemic and public health response[J]. Br Med Bull, 2016, 117(1): 15-23.
[45]	Centers for Diseases Control and Prevention. Zika virus research pays it forward[EB/OL]. (2019-12-09)[2024-03-27]. https://www.cdc.gov/globalhealth/healthprotection/fieldupdates/fall-2019/zika-virus-research.html.
[46]	Horefti E. The importance of the one health concept in combating zoonoses[J]. Pathogens, 2023, 12(8): 977.

新发传染病全球大流行的挑战与跨部门综合防控策略

Challenges of the global pandemics of emerging infectious diseases and integrated intersectoral prevention strategy

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 2

参考文献 46

相关文章 14

编辑推荐

Metrics

本文评价

[1]	费思伟, 赵翰卿, 尹静娴, 孙芷珊, 郭晓奎, KASSEGNE Kokouvi, 周晓农. 基于文献计量分析的蜱及蜱传疾病研究领域发展趋势[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(5): 609-618.
[2]	倪碧娴, 徐祥珍, 张强, 唐凤, 张嘉尧, 茅范贞, 戴洋, 刘耀宝, 曹俊. 2015—2022年江苏省棘球蚴病网络报告病例流行病学特征分析[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(5): 636-639.
[3]	晁安琪, 李慧敏, 胡沁沁, 周晓农, 郭晓奎, 殷堃. 基于全健康理念的气候变化下人兽共患病防控策略[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(3): 263-269.
[4]	陈琳, 朱继峰, 邱竞帆, 徐志鹏, 张东辉, 陈璐, 何健, 李伟, 杨坤, 季旻珺. 寓全健康理念于血吸虫病防控虚拟仿真项目建设[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(1): 81-84.
[5]	王晨曦, 陈福民, 修乐山, 胡沁沁, 周晓农, 郭晓奎, 殷堃. 基于全健康理念的气候变化下人兽共患病风险监测预警体系[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(6): 691-700.
[6]	李慧敏, 刘婧姝, 王希涵, 赵翰卿, 解艺, 尹静娴, 吕超, 周楠, 蒋天哥, 谷思雨, 殷堃, 周晓农, 郭晓奎, 胡沁沁. 基于全健康理念的新发传染病综合监测预警体系：结构与创新[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(5): 572-578.
[7]	李真, 郭晓奎, 王月祥, 郑彬, 周晓农. 基于SWOT分析的中国全健康发展策略研究[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(3): 271-277.
[8]	罗卓韦, 周正斌, 公衍峰, 冯家鑫, 李元元, 张仪, 李石柱. 我国内脏利什曼病的流行现状和防控挑战[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(2): 146-152.
[9]	刘婧姝, 张晓溪, 郭晓奎. 全健康的起源、内涵及展望[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(1): 1-11.
[10]	周晓农. 以全健康理念推进人兽共患病预防与控制[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(1): 12-19.
[11]	沈玉娟, 姜岩岩, 曹建平. 我国介水传播肠道原虫病流行现状与防控策略[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(1): 8-12.
[12]	王金玲, 吴周伟, 赵思琪, 赵忠顺, 毛艳敏. 2005-2018年连云港市输入性疟疾疫情与防控策略分析[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(5): 545-551.
[13]	汪天平*，操治国. 中国棘球蚴病防控进展及其存在的问题[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(3): 15-291-296.
[14]	许光荣1，张丽杰2，曾光2 *. 2006-2011年四川省甘孜州棘球蚴病疫情分析[J]. 中国寄生虫学与寄生虫病杂志, 2013, 31(3): 14-224-228.