CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2021 , Vol. 39 >Issue 5: 617 - 620

DOI: https://doi.org/10.12140/j.issn.1000-7423.2021.05.009

NEW VISION

Influence of nutritional metabolism of Anopheles on its transmission capability of malaria parasites

  • Xiu-mei SONG ,
  • Jing-wen WANG
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  • 1 School of Life Sciences, Fudan University, Shanghai 200438, China
    2 Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200438, China

Received date: 2021-10-11

  Revised date: 2021-10-26

  Online published: 2021-11-10

Supported by

National Natural Science Foundation of China(31822051);National Natural Science Foundation of China(U1902211);National Institutes of Health Research Grant Program(R01AI129819)

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Abstract

Nutritional metabolism of mosquitoes provides a variety of nutrients and signaling molecules to ensure their growth, development and reproduction. At the same time, malaria parasites utilize Anopheles’ nutritional metabolism for acquisition of nutrients to ensure their own development and proliferation. Up to now, little is known regarding the impact of malaria parasite invasion on Anopheles host metabolism, and how mosquito metabolism affects itself reproduction, immune response and other physiological changes during pathogenic invasion. This review summarizes the interplay between Anopheles metabolism and malaria parasite from the aspects of metabolism of glucose, lipids and amino acids, to provide clues for development of mosquito-borne infectious diseases.

Key words： Anopheles; Malaria parasites; Metabolism

Cite this article

Xiu-mei SONG , Jing-wen WANG . Influence of nutritional metabolism of Anopheles on its transmission capability of malaria parasites[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021 , 39(5) : 617 -620 . DOI: 10.12140/j.issn.1000-7423.2021.05.009

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