CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2021 , Vol. 39 >Issue 4: 553 - 556

DOI: https://doi.org/10.12140/j.issn.1000-7423.2021.04.022

SHORT COMMUNICATIONS

Laboratory diagnosis of two misdiagnosed imported Plasmodium ovale malaria cases in Shanghai

  • Yao-guang ZHANG ,
  • Li JIANG ,
  • Zhen-yu WANG ,
  • Min ZHU ,
  • Qian ZHU ,
  • Xiao-Jiang MA ,
  • Huan-yu WU
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  • Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China

Received date: 2020-12-21

  Revised date: 2021-07-01

  Online published: 2021-08-11

Supported by

Shanghai "Science and Technology Innovation Action Plan" Project(20DZ2200300);Fifth Round of Three-year Action Plan Key Discipline Project for Public Health System Construction of Shanghai Municipal Government(GWV-10.1-XK13)

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Abstract

Laboratory diagnosis was performed using microscopic examination, rapid malaria diagnostic test (RDT) and malaria nucleic acid test (NP-2002 method, multiplex PCR method and qPCR method) on two blood samples of imported malaria patients, to which there was controversy on the Plasmodium species. The initial examination of case 1 in a district-level center for disease control and prevention (CDC) in region A found P. falciparum (Pf) by microscopy, and Pf by RDT, whereas nucleic acid test was not done. The examination result was rechecked by Shanghai Municipal Center for Disease Control and Prevention (SCDC), presenting confirmation of P. ovale (Po) by microscopy, Pf by RDT, and Po by nucleic acid detection. The initial examination results of case 2 using microscopy, RDT, and nucleic acid detection in the district B CDC all revealed P. vivax (Pv). The recheck results of SCDC were Po by microscopy, negative finding by RDT, and Po by nucleic acid detection.

Key words： Imported malaria; Plasmodium ovale; Microscopic examination; Rapid malaria diagnostic test; Nucleic acid test

Cite this article

Yao-guang ZHANG , Li JIANG , Zhen-yu WANG , Min ZHU , Qian ZHU , Xiao-Jiang MA , Huan-yu WU . Laboratory diagnosis of two misdiagnosed imported Plasmodium ovale malaria cases in Shanghai[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021 , 39(4) : 553 -556 . DOI: 10.12140/j.issn.1000-7423.2021.04.022

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