Abstract: A. comprehensive survey was carried out in 8 selected sites in 4 counties of Xizang Autonomous Region to disclose human parasite distribution in the local inhabitants. A total of 2746 stool specimens and 463 serum samples were examined for parasite infection, whereas anal scraping by using adhesive-tape was preformed on 78 children for detecting Enterobius vermictilaris. Altogether, 21 species of parasite were discovered. The result indicated that geographic and environmental features, socioeconomic status, sanitary conditions, education and age were important factors affecting the distribution of parasitic infections.