Abstract: An investigation on soil transmitted nematode infections was carried out in 22 056 people in 42 pilot sites of 10 counties/cities, Henan Province during 1988-1990. The overall infection rate was 61.9%. Five species of soil transmitted nematodes were detected, including Ascaris lumbricoides 40.7%, hookworm 9.2%, Trichuris trichiura 2.3%, Enterobius vermi cularis (below 12 years old) 21.8%, and Strongyloides stercoralis 0.02%. As females contact more frequently with fecal fertilizer during farming, the infection rate of hookworm was significantly higher in them than in males. Pre school children and juveniles were the most vulnerable age groups, so pupils and middle school students showed the highest infection rate as compared with other occupations; the situation is attributed to the poor personal hygiene.