›› 1995, Vol. 13 ›› Issue (1): 35-38.
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Abstract: The capacity of mitogen Con A and SEA stimulated spleen cells to produce cytokines IFN γ and IL 2 was studied in S.japonicum infected mice every two weeks from o to 14 wk after infection. The results showed that the levels of these two cytokines began to rise at the 4th wk after infection and reached a peak level at 6 8 wk, then declined to the levels similar to those pre infection at 12 14 wk after infection. The IFN γ level reached the peak earlier than the IL 2 level. The dynamics of cytokine level in both mitogen and antigen stimulated group was similar. The results suggest that IL 2 and IFN γ might be the essential cytokines involved in egg granuloma formation in schistosomiasis japonica.
CLC Number:
R532.210.2
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https://www.jsczz.cn/EN/Y1995/V13/I1/35