Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

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Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

GONG Qing-long, WANG Chun-feng, YANG Gui-lian*

College of Animal Science and Technology，Jilin Agricultural University；Jilin Provincial Engineering Research Center of Animal Probiotics，Changchun 130118，China

Online:2016-04-30 Published:2016-06-30

Abstract

Abstract: Schistosomes interfere with the primary coagulation, secondary coagulation, and vascular endothelial functions of the host, and activate the fibrinolytic activity, which indicate the presence of anti-coagulation effect during schistosome parasitism. This review introduces research progress on the anti-coagulation mechanisms of schistosomes, in the aim to provide theoretical basis for development of antibodies against schistosome and novel anti-thrombotic or thrombolytic drugs.

Key words: Schistosome, Anti-coagulation, Platelet, Fibrinolysis

GONG Qing-long, WANG Chun-feng, YANG Gui-lian*. Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes[J]. .

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Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

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