Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

GONG Qing-long, WANG Chun-feng, YANG Gui-lian*

College of Animal Science and Technology，Jilin Agricultural University；Jilin Provincial Engineering Research Center of Animal Probiotics，Changchun 130118，China

Online:2016-04-30 Published:2016-06-30

Abstract

Abstract: Schistosomes interfere with the primary coagulation, secondary coagulation, and vascular endothelial functions of the host, and activate the fibrinolytic activity, which indicate the presence of anti-coagulation effect during schistosome parasitism. This review introduces research progress on the anti-coagulation mechanisms of schistosomes, in the aim to provide theoretical basis for development of antibodies against schistosome and novel anti-thrombotic or thrombolytic drugs.

Key words: Schistosome, Anti-coagulation, Platelet, Fibrinolysis

GONG Qing-long, WANG Chun-feng, YANG Gui-lian*. Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes[J]. .

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Research Progress on the Mechanisms of Impediment of Blood Coagulation in Host by Adult Schistosomes

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