Course of malaria control and elimination in Hubei Province

doi:10.12140/j.issn.1000-7423.2021.05.001

Abstract

Abstract:

Historically, vivax malaria has been dominantly prevalent in Hubei Province, transmitted by the vectors Anopheles sinensis and An. anthropophagus. Two major outbreaks of malaria had occurred in Hubei Province in 1954—1955 and 1967—1973, with the incidence in 1970 reached to high as 602.4/10 000. Over the past 70 years, following the principle of "adapting measures to local conditions, classified guidance and highlighting key points", different comprehensive measures have been applied in Hubei Province, and the incidence of malaria dropped to 0.07/10 000 by 2010. In 2010, Hubei Province launched an action plan to eliminate malaria. Since 2013, no indigenous case has been reported. In 2019, the province passed appraisal of malaria elimination, achieving the goal of malaria eliminated in the whole province. This review summarizes the endemic status of and control efforts for malaria, the course of elimination work, and the challenges encountered, as well as prospects in this regard in Hubei Province.

Key words: Malaria, Control, Elimination, Prevention, Hubei Province

CLC Number:

R531.3

XIA Jing, WU Dong-ni, ZHU Hong, WANG Lun, ZHANG Juan, LIN Wen, LI Kai-jie, CAO Mu-min, LIU Si, ZHANG Hua-xun. Course of malaria control and elimination in Hubei Province[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(5): 565-571.

Figures/Tables 3

References 30

[1]	Huang GQ, Yan BW, Yuan FY, et al. Thirty-year experience of malaria control in Hubei Province[J]. J Public Health Prev Med, 2004, 15(6):66-68. (in Chinese)
	( 黄光全, 严本武, 袁方玉, 等. 湖北省疟疾联防30年成绩与经验[J]. 公共卫生与预防医学, 2004, 15(6):66-68.)
[2]	Xia J, Zhang HX, Lin W, et al. Mid-term assessment report of Malaria Elimination Action Plan in Hubei[J]. Chin Trop Med, 2018, 18(4):308-311. (in Chinese)
	( 夏菁, 张华勋, 林文, 等. 湖北省消除疟疾行动计划中期评估报告[J]. 中国热带医学, 2018, 18(4):308-311.)
[3]	Zhang HX, Huang GQ, Lin W, et al. Analysis of epidemic posture of malaria from 1971 to 1997 in Hubei Province[J]. Hubei J Prev Med, 1999, 10(3):15-16, 18. (in Chinese)
	( 张华勋, 黄光全, 陈国英, 等. 湖北省1971—1997年疟疾流行态势分析[J]. 湖北预防医学杂志, 1999, 10(3):15-16, 18.)
[4]	Pei SJ, Huang GQ, Gui AF, et al. Analysis of malaria epidemic situation in the past ten years in Hubei Province[J]. J Public Health Prev Med, 2004, 15(6):12-14. (in Chinese)
	( 裴速建, 黄光全, 桂爱芳, 等. 湖北省近10年疟疾流行态势分析[J]. 公共卫生与预防医学, 2004, 15(6):12-14.)
[5]	Xia J, Cai S X, Lin W, et al. Epidemiological analysis of malaria prevalence in Hubei Province from 2010 to 2014[J]. Chin J Schisto Control, 2016, 28(3):247-257. (in Chinese)
	( 夏菁, 蔡顺祥, 林文, 等. 2010—2014年湖北省疟疾疫情流行病学分析[J]. 中国血吸虫病防治杂志, 2016, 28(3):247-251, 257.)
[6]	Li KJ, Cai SX, Lin W, et al. Analysis of malaria epidemic situation and control in Hubei Province from 1974 to 2015[J]. Chin J Schisto Control, 2016, 28(4):393-396. (in Chinese)
	( 李凯杰, 蔡顺祥, 林文, 等. 1974—2015年湖北省疟疾流行与防治分析[J]. 中国血吸虫病防治杂志, 2016, 28(4):393-396.)
[7]	Huang GQ, Zhang HX, Liu JY, et al. Study on the ecology character of distribution and role of malarial transmission in Anopheles anthropophagus in Hubei, China[J]. 2000, 11(3):208-212. (in Chinese)
	( 黄光全, 张华勋, 刘井元, 等. 湖北省嗜人按蚊分布、生态与传疟作用研究[J]. 中国媒介生物学及控制杂志, 2000, 11(3):208-212.)
[8]	Zhou XN. Roadmap analysis on malaria elimination in China[M]. Shanghai: Shanghai Science & Technology Press, 2019: 155. (in Chinese)
	( 周晓农. 中国消除疟疾路径分析报告[M]. 上海: 上海科学技术出版社, 2019: 155.)
[9]	Yuan FY, Huang GQ, Xu BZ. The effect observation of bednets impregnated with deltamethrin for the control of the malaria vector and malaria in Hubei Province for four consecutive years[J]. Chin J Parasit Dis Con, 1995, 8(4):241-243. (in Chinese)
	( 袁方玉, 黄光全, 徐博钊. 湖北省连续四年溴氰菊酯浸泡蚊帐防制媒介和控制疟疾流行的效果观察[J]. 中国寄生虫病防治杂志, 1995, 8(4):241-243.)
[10]	Yuan FY, Huang GQ, Zhang HX, et al. Status of malaria epidemic and feasibility of malaria elimination in Hubei[J]. J Public Health and Prev Med, 2010, 21(4):28-30. (in Chinese)
	( 袁方玉, 黄光全, 张华勋, 等. 湖北省疟疾流行现状与消除疟疾的可能性分析[J]. 公共卫生与预防医学, 2010, 21(4):28-30.)
[11]	Cao J, Zhou SS, Zhou HY, et al. Malaria from control to elimination in China: transition of goal, strategy and interventions[J]. Chin J Schisto Control, 2013, 25(5):439-443. (in Chinese)
	( 曹俊, 周水森, 周华云, 等. 中国疟疾从控制走向消除——消除阶段的目标策略和措施[J]. 中国血吸虫病防治杂志, 2013, 25(5):439-443.)
[12]	Zhang C, Liu JY, Wan L, et al. Epidemic analysis of malaria surveillance sites in Hubei Province from 2012 to 2014[J]. J Hubei Univ Chin Med, 2015, 17(3):110-112.)
	( 张聪, 刘井元, 万伦, 等. 2012—2014年湖北省疟疾监测点疫情分析[J]. 湖北中医药大学学报, 2015, 17(3):110-112.)
[13]	Li KJ, Shang XP, Pi Q, et al. Analysis on the density and ecological habit of the main malaria vector Anopheles in Hubei Province[J]. Int J Med Parasit Dis, 2015, 42(6):328-331. (in Chinese)
	( 李凯杰, 尚晓鹏, 皮琦, 等. 湖北省主要传疟媒介按蚊生态习性及密度分析[J]. 国际医学寄生虫病杂志, 2015, 42(6):328-331.)
[14]	Zhang HX, Li KJ, Hu LQ, et al. Monitoring of resistance of Anopheles sinensis to normal insecticide[J]. Chin Trop Med, 2010, 10(4):400-401. (in Chinese)
	( 张华勋, 李凯杰, 胡乐群, 等. 中华按蚊对常用杀虫剂的抗药性监测[J]. 中国热带医学, 2010, 10(4):400-401.)
[15]	Pei SJ, Zhang HX, Li KJ, et al. Monitoring of resistance of Anopheles sinensis to deltamethrin in Hubei Province, China[J]. Chin J Vector Biol Cont, 2014, 25(1):18-20. (in Chinese)
	( 裴速建, 张华勋, 李凯杰, 等. 湖北省中华按蚊对溴氰菊酯的抗药性监测[J]. 中国媒介生物学及控制杂志, 2014, 25(1):18-20.)
[16]	Huang GQ, Hu LQ, Zhang HX, et al. Potential infection of imported malaria and control measures in Hubei Province[J]. Chin Trop Med, 2013, 13(12):1490-1493. (in Chinese)
	( 黄光全, 胡乐群, 张华勋, 等. 湖北省输入性疟疾发病态势及防控措施分析[J]. 中国热带医学, 2013, 13(12):1490-1493.)
[17]	Xia J, Huang XB, Sun LC, et al. Epidemiological characteristics of malaria from control to elimination in Hubei Province, China, 2005—2016[J]. Malar J, 2018, 17:81. doi: 10.1186/s12936-018-2207-7
[18]	Xia J, Zhang HX, Liu S, et al. Epidemiological analysis of malaria in Hubei Province from 2015 to 2018[J]. Chin J Parasitol Parasit Dis, 2020, 38(3):1-7. (in Chinese)
	( 夏菁, 张华勋, 刘斯, 等. 2015—2018年湖北省报告疟疾疫情分析[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(4):429-434.)
[19]	Wu DN, Xia J, Sun LC, et al. Epidemic characteristics of imported malaria in Hubei, 2015—2019[J]. Chin Trop Med, 2021, 21(1):19-23. (in Chinese)
	( 吴冬妮, 夏菁, 孙凌聪, 等. 湖北省2015—2019年输入性疟疾流行特征[J]. 中国热带医学, 2021, 21(1):19-23.)
[20]	Lin W, Mao ZF. Analysis of malaria epidemic in Hubei Province (2009—2011)[J]. J Pub Health Prev Med, 2012, 23(2):15-17. (in Chinese)
	( 林文, 毛宗福. 湖北省2009—2011年疟疾疫情分析[J]. 公共卫生与预防医学, 2012, 23(2):15-17.)
[21]	Xia J, Cai SX, Zhang HX, et al. Spatial, temporal and spatiotemporal analysis of malaria in Hubei Province, China from 2004—2011[J]. Malar J, 2015, 14:145. doi: 10.1186/s12936-015-0650-2
[22]	Lin CY, Chen Z, Wang SQ, et al. Investigation of a rare local epidemic of Plasmodium malariae infection in Sanya City, Hainan Province[J]. Chin Trop Med, 2016, 16(5):481-484. (in Chinese)
	( 林常勇, 陈朱, 王善青, 等. 海南省三亚市一起罕见的当地三日疟疫情分析及处置[J]. 中国热带医学, 2016, 16(5):481-484.
[23]	Sun YW, Yu DM, Chen J, et al. Two individual incidences of vivax malaria in Dandong municipality of Liaoning Province[J]. Chin J Pub Health, 2017, 33(2):314-316. (in Chinese)
	( 孙英伟, 于丹梅, 陈君, 等. 辽宁省丹东市两例间日疟病例报告疫情分析[J]. 中国公共卫生, 2017, 33(2):314-316.)
[24]	Feng J, Zhou SS. From control to elimination: the historical retrospect of malaria control and prevention in China[J]. Chin J Parasitol Parasit Dis, 2019, 37(5):505-513. (in Chinese)
	( 丰俊, 周水森. 从控制走向消除: 我国疟疾防控的历史回顾[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(5):505-513.)
[25]	From elimination to post-elimination: characteristics,challenges and re-transmission preventing strategy of imported malaria in China[J]. Chin Trop Med, 2021, 21(1):5-10. (in Chinese)
	( 丰俊, 张丽, 涂宏, 等. 从消除到消除后: 中国输入性疟疾的疫情特征、挑战及防止再传播策略[J]. 中国热带医学, 2021, 21(1):5-10.)
[26]	National Health Commission of the People’s Republic of China. Management Measure for Prevent Re-establishment of Malaria[EB/OL]. (2020-12-31)[2021-01-06]. http://www.nhc.gov.cn/jkj/s3577/202101/1c8b2c40c76a4815acd703f13dba0b83.shtml.
	(中华人民共和国国家卫生健康委员会. 关于印发《防止疟疾输入再传播管理办法》的通知[EB/OL]. (2020-12-31)[2021-01-06]. http://www.nhc.gov.cn/jkj/s3577/202101/1c8b2c40c76a-4815acd703f13dba0b83.shtml.
[27]	Li KJ, Huang GQ, Zhang HX, et al. Epidemic situation and control strategy of imported malaria in Hubei Province from 2006 to 2011[J]. Chin J Schisto Control, 2013, 25(3):259-262. (in Chinese)
	( 李凯杰, 黄光全, 张华勋, 等. 2006—2011年湖北省输入性疟疾疫情分析及防控策略[J]. 中国血吸虫病防治杂志, 2013, 25(3):259-262.)
[28]	Xia J, Wu DN, Wu K, et al. Epidemiology of Plasmodium falciparum malaria and risk factors for severe disease in Hubei Province, China[J]. Am J Trop Med Hyg, 2020, 1(4):1534-1539.
[29]	Investigation and analysis of malaria prevention and control measures for migrant workers to high prevalence area in Hubei Province[J]. J Pub Health Prev Med, 2014, 25(3):30-33. (in Chinese)
	( 黄光全, 李凯杰, 张华勋, 等. 湖北省赴高疟区务工人员疟疾防控现状调查[J]. 公共卫生与预防医学, 2014, 25(3):30-33.)
[30]	Cao J, Liu YB, Cao YY, et al. Sustained challenge to malaria elimination in China: imported malaria[J]. Chin J Parasitol Parasit Dis, 2018, 36(2):93-96. (in Chinese)
	( 曹俊, 刘耀宝, 曹园园, 等. 中国消除疟疾的持续挑战: 输入性疟疾[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(2):93-96.)

国家	疟疾分型					合计
国家	恶性疟	间日疟	卵型疟	三日疟	混合感染	合计
非洲
刚果（金）	126	3	14	3	0	146
尼日利亚	107	3	11	2	1	124
安哥拉	76	1	10	5	0	92
埃塞俄比亚	7	71	1	0	1	80
利比里亚	44	5	4	3	0	56
刚果（布）	42	2	8	3	1	56
几内亚	44	4	4	2	0	54
加纳	39	2	6	1	0	48
赤道几内亚	33	5	8	1	0	47
乌干达	33	2	6	1	0	42
赞比亚	34	1	4	0	0	39
莫桑比克	33	0	4	1	0	38
喀麦隆	27	2	6	2	0	37
坦桑尼亚	26	1	4	1	0	32
科特迪瓦	22	0	5	0	0	27
加蓬	14	4	4	0	0	22
其他（17个）	84	7	11	2	0	104
亚洲
缅甸	3	31	0	2	0	36
巴基斯坦	0	26	0	0	0	26
柬埔寨	1	20	0	0	0	21
印度尼西亚	3	12	0	0	0	15
老挝	2	3	0	0	0	5
其他（4个）	1	2	2	0	0	5
大洋洲
巴布亚新几内亚	0	2	0	1	0	3
南美洲
圭亚那	1	2	0	0	0	3
合计	802	211	112	30	3	1 158