Status of Toxoplasma infection in pregnant and postpartum women in Duyun district of Guizhou Province during 2015-2018

doi:10.12140/j.issn.1000-7423.2020.02.020

Abstract

Abstract:

To investigate the status of Toxoplasma infection in pregnant and postpartum women in Duyun district of Guizhou Province, China, serum samples were collected during 2015-2018 from pregnant and postpartum women receiving regular checkups and the women who had pathological pregnancies such as miscarriage, stillbirth, and deformity in Qiannan People′s Hospital, to test for specific IgM and IgG antibodies against Toxoplasma by ELISA. SPSS 17.0 software was used for statistical analysis. The positive rates of serum Toxoplasma antibody were compared by chi-square test. A total of 6 931 pregnant and postpartum women participated in the survey, including 6 825 normal pregnancies and parturients, and 106 pathological pregnancies and parturients. The age of the participants ranged 18-45 years, with ethnicities mainly of Han, Buyi, and Miao. The overall positive rate of Toxoplasma antibody was 6.1%(424/6 931), composed of 5.9%(403/6 825) in normal pregnant and postpartum women, and 19.8% (21/106) in pathological pregnancies and parturients (P < 0.01). There was a significant difference in the positive rate of Toxoplasma antibody among Han (7.5%, 215/2 886), Miao (5.4%, 132/2 453), Buyi (5.5%, 71/1 300), Shui (2.3%, 3/131), Tujia (2.0%, 2/100) and Dong (1.6%, 1/61) ethnicities (P < 0.05). There was also a significant difference in the positive rate of Toxoplasma antibody among cadres (1.3%, 22/1 714), teachers (1.8%, 22/1 216), rural workers (13.2%, 320/2 418) and other occupations (3.8%, 60/1 583) (P < 0.01). It was noted that the pregnant women with and without history of contacting with animals was 26.2% (361/1 379) and 1.1% (63/552), respectively, with the difference being statistically significant(P < 0.01). The results demonstrate the pregnant women with positive Toxoplasma antibody in Duyun District of Guizhou Province are mainly those having pathological pregnancyies, being Han ethnicity, engaging in rural farming work, and having contacts with animals.

Key words: Toxoplasma, Infection, Pregnant and puerperal women, Duyun, Guizhou

CLC Number:

R531.8

Xiao-qing XU, De-jun LIAO, Xia FENG, Ru-feng XIAO, Jian JIANG. Status of Toxoplasma infection in pregnant and postpartum women in Duyun district of Guizhou Province during 2015-2018[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(2): 165-167.

References 10

[1]	National Office of Investigation on the Status of Human Parasitic Diseases. National investigation on the status of human parasitic diseases[J]. Chin J Parasitol Parasit Dis, 2005,23(suppl):332-340. (in Chinese)
	( 全国人体重要寄生虫病现状调查办公室. 全国人体重要寄生虫病现状调查[J]. 中国寄生虫学与寄生虫病杂志, 2005,23(增刊):332-340.)
[2]	Gu XY, Zhao XX . Research progress of infection with Toxoplasma gondii during pregnancy[J]. Chin J Obstet Gynecol Pediatr Electron Ed, 2015,11(5):660-662. (in Chinese)
	( 谷孝月, 赵晓曦 . 孕期弓形虫感染的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2015,11(5):660-662.)
[3]	Health and Family Planning Commission of the people’s Republic of China. WS/T 486-2015 diagnosis of Toxoplasmosis [S]. Beijing: China Standard Press, 2015. ( in Chinese)
	( 中华人民共和国卫生和计划生育委员会. WS/T 486-2015弓形虫病的诊断[S].北京: 中国标准出版社, 2015. )
[4]	Wen LY, Xiong YH, Yan XL , et al. Reply to “Discussion on the insufficiency of criteria for diagnosis of toxoplasmosis (WS/T 486-2015) and treatment of Toxoplasma gondii infection in pregnancy”[J]. Chin J Parasitol Parasit Dis, 2017,35(4):390-392. (in Chinese)
	( 闻礼永, 熊彦红, 严晓岚 , 等. 对“试论《弓形虫病的诊断》(WS/T 486-2015)标准的不足并探讨孕妇弓形虫感染的处理”一文的回复[J]. 中国寄生虫学与寄生虫病杂志, 2017,35(4):390-392.)
[5]	Logar J, Storman A, Permru-Sreson T , Diagnosis and management of congenital toxoplasmosis in slovenia[J] Clin Microbiol infec, 2006,12(Suppl 4):2208.
[6]	Xu Q, Hua HY . Impact of past Toxoplasma gondii infection on the fetus during pregnancy[J]. Chin J Schisto Control, 2010,22(2):187-188. (in Chinese)
	( 许倩, 华海涌 . 弓形虫既往感染在孕期内对胎儿的影响[J]. 中国血吸虫病防治杂志, 2010,22(2):187-188.)
[7]	Lai ZF, Chen RL, Niu JF , et al. Investigation of Toxoplasma gondii infection in pregnant women in Shenzhen City[J]. J Trop Med, 2016,16(12):1562-1564. (in Chinese)
	( 赖植发, 陈润莉, 牛姬飞 , 等. 深圳市孕妇弓形虫感染调查[J]. 热带医学杂志, 2016,16(12):1562-1564.)
[8]	Guo YL, Zou YG, Xu DC , et al. Analyais of Toxoplasma gondii infection and related factors among special population in Changzhou City, Jiangsu Province[J]. Chin J Schisto Control, 2016,28(6):669-673, 698. (in Chinese)
	( 郭燕丽, 邹永根, 许大成 , 等. 江苏省常州市特殊人群弓形虫感染调查及影响因素分析[J]. 中国血吸虫病防治杂志, 2016,28(6):669-673, 698.)
[9]	Yang WL, Wang Y . Investigation on Toxoplasma gondii infection in childbearing age and pregnant women in Langfang City, Hebei Province[J]. Chin J Schisto Control, 2016,28(2):210-211. (in Chinese)
	( 杨文丽, 王英 . 河北省廊坊市育龄期妇女与孕妇弓形虫感染状况调查[J]. 中国血吸虫病防治杂志, 2016,28(2):210-211.)
[10]	Hou LP, Zhang HF, Rao HX , et al. A cross-sectional survey of Toxoplasma gondii infection in pregnant women of Taiyuan[J]. J Pathog Biol, 2015,10(1):100-101. (in Chinese)
	( 侯丽萍, 张慧芳, 饶华祥 , 等. 太原市孕妇弓形虫感染现况调查[J]. 中国病原生物学杂志, 2015,10(1):100-101.)

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