Research advances on the relationship between cestode excretory/secretory products and host immune response

doi:10.12140/j.issn.1000-7423.2020.01.020

Abstract

Abstract: Cestodes are common zoonotic parasites. The excretory/secretory products (ESPs) of cestodes are produced during the infection and exposed directly to the host immune system, being one of the most possible effectors causing the changes of host immune responses. In recent years, a wealth of studies have shown that ESPs can induce and regulate the host immune responses, which are closely related to the cestodes infection. Cestodes ESPs can induce host’s positive immune response to control the infection, and also induce negative immune response, enabling the cestodes to evade the host immune attacks. thus resulting in establishment of a long-time infection. This paper presents a brief review on the relations between cestode ESPs and host immune response.

Key words: Cestode, Excretory/secretory product, Immunological effect

CLC Number:

R383.3

FAN Xian-min, ZHOU Bi-ying. Research advances on the relationship between cestode excretory/secretory products and host immune response[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(1): 128-133.

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