Epidemiological investigation of hepatic echinococcosis in human population in Jiuzhi, Qinghai Province in 2018

doi:10.12140/j.issn.1000-7423.2019.06.011

Abstract

Abstract:

Objective To investigate the endemic status and distribution of hepatic hydatidosis in Jigzhi County, Qinghai Province. Methods Six natural villages (or towns), including Zhiqingsongduo, Mentang, Baiyu, Suohurima, Wa’eryi and Wasai, were selected as survey sites from July to December, 2018. Abdominal ultrasound examination was performed in full-time residents with age over 6 years old. Anti-Echinococcus IgG was detected in the sera from the villagers who were willing to donate blood by ELISA. The endemic status of hepatic hydatidosis in Jiuzhi population was analyzed. Results A total of 23 505 subjects underwent the abdominal ultrasound examination, 345 of them were diagnosed as hepatic hydatidosis with the detection rate of 1.47%, of which 126 as hepatic cystic echinococcosis (0.54%) and 219 as hepatic alveolar echinococcosis (0.93%), with higher prevalence of hepatic alveolar echinococcosis than that of cystic echinococcosis(P < 0.05). The prevalence of hepatic hydatidosis in male (0.86%, 99/11 560) was lower than that in female (2.06%, 246/11 945) with significant difference (P < 0.01). Wa’eryi and Baiyu villages in Jiuzhi County owned the higher prevalence of 3.89% (147/3 782) and 3.01% (149/4 949), respectively, than the rest villages (χ²= 277.926, P < 0.01). Regarding the occupation, self-employed businessmen/the unemployed and those doing housework showed the higher prevalence of 20.40% (20/98) and 17.39% (60/345) compared with other occupational groups (P < 0.05). Those with age within 20-29 and 30-39 years old had the higher prevalence of 2.01% (112/5 563) and 2.16% (189/8 756), respectively, with significant differences compared to other age groups (P < 0.01). Among all subjects, 7 845 were involved in the ELISA assay for testing serological anti-Echinococcus IgG and 2 305 of them were antibody positive with the positive rate of 29.38%. The positive rate of anti-Echinococcus IgG was 100% in 107 cases confirmed by the abdominal ultrasound examination. Among 126 cases with hepatic cystic echinococcosis, 49 of them had cyst over 10 cm in diameter (38.9%). Among 219 cases with hepatic alveolar echinococcosis, 116 presented the infiltrating type, 34 calcified and 69 with liquid/cavitary type. Conclusion The prevalence of hepatic echinococcosis is still high in the population in Jiuzhi, Qinghai, with mixed cystic and alveolar echinococcosis. Alveolar echinococcosis was dominant in this endemic county. People with middle age, female, working at home or other business, living in Wa’eryi and Baiyu villagers had the highest prevalence of hepatic hydatidosis and should be the main target for treatment and prevention.

Key words: Echinococcusis, Epidemiology, Jiuzhi County

CLC Number:

R532.32

Wei GAO, Hao WANG, You-liang MA, Shun-yun ZHAO, Ajide, Jin-yu YANG. Epidemiological investigation of hepatic echinococcosis in human population in Jiuzhi, Qinghai Province in 2018[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2019, 37(6): 681-684.

Figures/Tables 1

References 18

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特征 Feature	检查人数 No. exam’d	棘球蚴病Echinococcosis		细粒棘球蚴病Cystic echinococcosis		多房棘球蚴病 Alveolar echinococcosis
特征 Feature	检查人数 No. exam’d	患者数 No. case	检出率/% Prevalence/%	患者数 No. case	检出率/% Prevalence/%	患者数 No. case	检出率/% Prevalence/%
性别Gender
男性Male	11 560	99	0.85	33	0.29	66	0.57
女性Female	11 945	246	2.06	93	0.78	153	1.28
小计Subtotal	23 505	345	1.47	126	1.07	219	1.85
年龄Age group
6~10	689	4	0.58	2	0.29	2	0.29
11~19	2 176	11	0.51	4	0.18	7	0.32
20~29	5 536	112	0.22	31	0.56	81	1.46
30~39	8 756	189	1.28	77	0.88	112	1.28
40~49	4 356	24	0.55	9	0.21	15	0.34
50~59	1 176	2	0.17	1	0.09	1	0.09
60~65	789	3	0.38	2	0.25	1	0.13
小计Subtotal	23 505	345	1.47	126	0.54	219	0.93
地区Region
智青松多镇 Zhiqingsongduo	4 227	5	0.12	3	0.07	2	0.05
门堂乡Mentang	2 407	9	0.37	6	0.25	3	0.12
哇尔依乡 Wa’eryi	3 782	147	3.89	48	1.27	99	2.61
白玉乡Baiyu	4 949	149	3.01	48	0.97	101	2.04
哇赛乡 Wasai	3 671	19	0.52	12	0.33	7	0.19
索乎日麻乡Suohurima	4 469	16	0.36	9	0.20	7	0.16
小计Subtotal	23 505	345	1.47	126	0.54	219	0.93
职业Occupation
牧民Herdsmen	22 529	256	1.14	90	0.40	166	0.74
学生Student	213	4	1.88	3	1.40	1	0.47
干部Cadre	178	2	1.12	2	1.12	0	0
家务Houseworking	345	59	17.10	21	6.10	38	11.00
僧侣Monk	142	5	3.52	2	1.41	3	2.11
其他Other	98	19	19.39	8	8.16	11	11.22
小计Subtotal	23 505	345	1.47	126	0.54	219	0.93