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The Role of Adoptive Transfer of Immune Cells in Helminth-induced Regulation of Allergy and Autoimmune Diseases

DING Yi-han1,ZHOU rui2,YANG Xiao-di1*,ZHANG Li-li1   

  1. 1 Department of Microbiology and Parasitology,Anhui Key Laboratory of Infection and Immunity,Bengbu Medical College,Bengbu 233030,China;2 Department of Pediatrics,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China
  • Online:2015-08-30 Published:2015-09-10

Abstract:

Parasitic worms(helminth) or their derivates can inhibit allergy and autoimmune diseases by inducing the activation of immune cells and thus the release of regulatory factors. A large number of animal experiments have shown that adoptive transfer of lymphocytes can protect against immune deregulation and have potential clinical applications. In this review, we discuss the research progress on the role of adoptive transfer of immune cells in worm-induced regulation of allergy and autoimmune diseases.

Key words:  , Helminth;Adoptive transfer;Allergy and autoimmune diseases