›› 2011, Vol. 29 ›› Issue (3): 13-224-228,232.

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Application and Progress of Fluorescence in situ Hybridization in Schistosome Biology

 MO  Xiao-Jin, FENG  Zheng, HU  Wei   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Key Laboraory of Parasite and Vector Biology, MOH; WHO collaborating Center for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China
  • Online:2011-06-30 Published:2012-09-27

Abstract: Schistosomiasis is one of the most serious parasitic diseases. Schistosome genes research provides the basis for study of schistosomiasis diagnosis, vaccine and drug targets. Fluorescence in situ hybridization (FISH) in schistosome focuses on researches of location of functional genes on chromosomes, genome physical mapping and chromosome identification. This article reviews the application of FISH in schistosome biology and its potential development.

Key words: Schistosome, Fluorescence in situ hybridization, Functional gene, Location on chromosomes, Genome physical mapping