›› 2008, Vol. 26 ›› Issue (5): 14-386.

• 综述 • Previous Articles     Next Articles

Th17 in the Immunity Against Parasitic Infection

LIU Fan,YIN Hui-bin,SU Chuan*   

  1. Department of Pathogen Biology,Key Laboratory of Pathogen Biology of Jiangsu Province,Nanjing Medical University,Nanjing 210029,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-10-31 Published:2008-10-31
  • Contact: SU Chuan

Abstract: Th17 lymphocytes have been recently identified as a novel subset of CD4+ cells. It has been defined that IL-17,the main product of Th17, plays an important role in immunity against parasitic infection. There is a two-way infl-uence between Th17 and cytokine network: on one hand Th17 consummates cytokine network, on the other hand many cytokines regulate Th17’s activity in parasitic infection. In the anti-parasitic infection process, Th17 cells protect host or promote inflammation, even cause immune pathogenesis in different cases, which comprise host’s immune state, the burden of parasitic infection, as well as the treatment.

Key words: CD4+ T cell, Th17 cell, Anti-parasitic immunity