Abstract: Clinical data from 48 cases with cerebral schistosomiasis， who received surgery， were analyzed retrospectively. Surgical treatment was performed when the patient had the following conditions： mass focus confirmed by CT scanning， cranial hypertension， or ineffective drug therapy， or indistinguishable from glioma by iconographic diagnosis. Treatment of praziquantel was given when the patients got improved. Among the 48 patients with surgical treatment， 35 cases recovered， 8 showed an exacerbation of hemiparalysis， 5 had hemianesthesia， and epilepsy occurred in 2 cases， no cases died during or after the operation. Surgery combined with praziquantel therapy has been an effective way for the treatment of cerebral schistosomiasis.

Key words: Cerebral schistosomiasis, CT scanning, MRI scanning, Surgical treatment