›› 1998, Vol. 16 ›› Issue (2): 1-83.

• 论著 •     Next Articles

LONGITUDINAL SURVEILLANCE OF SENSITIVITY OF PLASMODIUM FALCIPARUM TO PYRONARIDINE IN SOUTH YUNNAN

Yang Henglin 1;Liu Dequan 2;Huang Kaiguo 1;Zhang Chunyong 2;Li Chunfu 1   

  1. 1 Institute of Malaria Prevention and Treatment of Yunnan Province,Simao 665000 2 Institute of Parasitic diseases; Chinese Academy of Preventive Medicine, Shangh 200025;
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-04-30 Published:1998-04-30

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Abstract:

AIM: To understand the changes in the sensitivity of Plasmodium falciparum to pyronaridine in the south of Yunnan Province. METHODS: WHO standard in vivo and in vitro microtest was used. RESULTS: In 1984-1985 and 1995, 36 and 39 cases of acute falciparum malaria were observed, the average defervescence time being 32 7±16 0 h and 56 2±27 4 h, the mean asexual parsite clearance time, 64 2±22 9 h and 55 3±11 8 h, and the recrudescence rate of patients followed up for 28 days, 15 2%(5/33) ...

Key words: Malaria, P.falciparum, in vivo, in vitro, assay, sensitivity, pyronaridine