›› 1997, Vol. 15 ›› Issue (6): 395-396.

• 实验报道 • Previous Articles     Next Articles

STUDY ON THE FUNCTION OF RED CELL IMMUNE ADHERENCE SYSTEM IN CYSTICERCOSISPATIENTS

Xu Zhijie1; Song Guiqin1; Zhao Yuying2; Wang Wenyu2   

  1. 1 Departmentof Parasitology, College of basic Medical Sciences, Harbin Medical University, Harbin 150086 2 Departmentof Immunology, Harbin Medical University, Harbin 150086
  • Received:1900-01-01 Revised:1900-01-01 Online:1997-12-28 Published:1997-12-28

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Abstract:

AIM:To investigate the changes and mechanism of red cell immune adherence function (RCIA) in cysticercosis patients. METHODS:The activity of C3b receptor on red blood cell membrance and the activity of regulated factor of RCIA were determined by yeast labelled technique. The levels of complement C3and circulated immune complex in sera from cysticercosis patients were determined by gel diffusion and PEG-UV spectrophotometry, respectively. RESULTS:The rate of red blood cell C3b receptor rosette and the activity of enhancing factor of RCIA in the cysticercosis patient group were markedly lower than those of the control group, while the rate of immune complex rosette, the activity of inhibiting factor of RCIA and the level of CIC in the patient group were significantly higher than those of the control group. CONCLUSION: In cysticercosis patients, the activity of C3b receptor in red cell membrance was affected and the ability of eliminating CIC was reduced.

Key words: Cysticercosis, red cell immune adherence（RCIA）