›› 1997, Vol. 15 ›› Issue (5): 276-280.

• 论著 • Previous Articles     Next Articles

EPIDEMIOLOGY AND POPULATION DYNAMICSOF HOOKWORM INFECTION IN A RURAL COMMUNITY OF NORTH JIANGSU PROVINCE

Zhang Tao1; Shen Yiping1; Yang Weiping2; Shao Jing ou3; Dong Kai4; Xu Juling2   

  1. 1 Departmentof Parasitology of Nanjing Medical University, Nanjing210029 2 Departmentof Parasitology of Medical College; Yangzhou University, Yangzhou225001 3　Institute of Antischistosomiasis of Yangzhou City, Yang zhou 2250014　Sanitary and Anti-epidemic Station of Jiangdu City, Jiangdu 225200
  • Received:1900-01-01 Revised:1900-01-01 Online:1997-10-30 Published:1997-10-30

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Abstract: AIM:To understand the population dynamics of hookworm infection and the effect of
chemotherapy on population transmission. METHODS:The mathematic model was used to simulate the
population dynamics of hookworm infection in the population of Groups A and B.RESULTS:The
changes in age- prevalence and ageintensity (EPG) profile rose with age; the negative binomial
probability model provided a good empirical description of the frequency distribution
ofhookworm burden per host,the K value was0.289 and 0.206, respectively in Groups A and B. There was a non-linear relation ship between worm burden and egg production and this showed density-dependent, the Z value was 0.919 and 0.899, respectively in Groups A and B. The basic reproductive rate R was 2.153 and 1.872, respectively in Groups A and B. CONCLUSION: When R value was greater than the transmission threshold (Ro= 1) , the endemicity of the hookworm infection was stable in the community; the difficulty of control programm emet was higher in the endemic area with high R than with low R, the effect of a single chemotherapy could not be consolidated with in a long period due to reinfection; the effectiveness of chemotherapy should be evaluated by examining the intensity of infection rather than overall prevalence.

Key words: Hookworm, infection, epidemiology, population dynamics, chemotherapy