›› 1997, Vol. 15 ›› Issue (2): 18-110.

• 论著 • Previous Articles     Next Articles

DETECTION OF CIRCULATING ANTIGENSIN ACUTE SCHISTOSOMIASIS PATIENTS AFTER TREATMENT

Wu Guilan, Wu Xiaolan   

  1. Wuhan Transportation Technology University Hospital, Wuhan 430063
  • Received:1900-01-01 Revised:1900-01-01 Online:1997-04-30 Published:1997-04-30

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Abstract:

AIM: To assess the therapeutic effect of praziquantel in treating acute schistosomiasis and provide evidence for further treatment. METHODS: Circulating antigens (CAg) detection method and etiological detection method. RESULTS: One hundred and ninety acute schistosomiasis patients were treated with praziquntel. After 0.5, 1.5, 3 and 4 years, their negative rate was 83.7%, 87.4%, 99.5% and 98.0%, respectively by fecal hatching method. Five years after treatment, the therapeutic efficacy was evaluated by CAg detection method. Of 164 schistosomiasis patients, 22 were positive (13.4%). As compared with etiological detection method, the coincident positive rate was 68.2%. CONCLUSION: The CAg detection method can reduce the diagnosis-missing rate and save time and labor. Especially, during the late period of the schistosomiasis prevention and treatment, this method can be used to evaluate the therapeutic effect of praziquantel and provide evidence for further treatment of patients.

Key words: Acute schistosomiasis japonica, detection of circulating antigens, follow-up of therapeutic efficacy