Abstract:

AIM:To study the clinical forms of cutaneous leishmaniasis (CL) basing on pathological changes in Karamay of Xinjiang. METHOD:Analysis on clinical and pathological data in 90 parasitologically confirmed CL cases in Karamay from 1988 to 1994. RESULTS:Cutaneous lesions were divided into 4 forms: papule,plaque,ulcerous nodule and nodular prurigo.Dermal pathological changes showed that the papule form and plaque form mainly consisted of accumulated macrophages and inflammatory cells induced by Leishmania . The skin surrounding the ulcerous nodule form presented necrosis,liquifaction and desquamation with Leishmania detected in the lesion.Nodular prurigo form was chiefly composed of epithelial cells,fibroblasts,giant cells and lymphocytes;a few Leishmania were found in the dermis.Normal blood picture was revealed in all cases.The size of spleen examined by B mode ultrasonography did not show marked difference comparing with the normal control.CONCLUSION:There are four forms of CL with different histopathological changes in Karamay of Xinjiang.