›› 1996, Vol. 14 ›› Issue (1): 54-57.

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STUDIES ON CELLULAR IMMUNITY OF MICE INFECTED WITH TOXOPLASMA GONDII AT EARLY STAGE

Wu Shaoting1, Lu Fangli2, Shi Youen2   

  1. 1 Sanitary and Anti epidemic Station of Shenzhen, Shenzhen 518020
    2 Department of Parasitology Tongji Medical University, Wuhan 430030
  • Online:1996-02-28 Published:2017-01-02

Abstract: AIM: To study the immune response of mice infected with Toxoplasma gondii. METHOD: Lymphocyte transformation test, determination of natural killer cell (NK) activity, tumor necrosis factor(TNF) and specific IgG antibody in serum. RESULTS: In the early stage after mice were infected with Toxoplasma gondii, the spleen lymphocyte response and NK actitity enhanced, and the quantity of TNF in serum increased but the level of IgG in serum remained unchanged. CONCLUSION: In the immune response of mice infected with  Toxoplasma gondii, the cellular immunity was more effective than the humoral immunity in the early stage in addition to their synergetic actions.

Key words: Toxoplasma gondii, cellular immunity, humoral immunity