›› 1995, Vol. 13 ›› Issue (3): 189-192.
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Abstract: Employing Capture ELISA, we determined the level of the circulating soluble egg antigen-antibody complex (SEAIC) in sera from mice infected with Schistosoma japonicum for 7 weeks and then treated the infected mice with praziquantel (100 mg/kg body weight). It was noted that the serum SEAIC level in treated mice dropped gradually after treatment. There was a significant decrease in 13 out of 15 mice in serum SEAIC levels at five weeks after treatment, OD value dropped from O. 358±0. 074 to 0.165±0. 049 (P0. 01). The serum SEAIC level in 10 mice declined to disappear (OD0.097) by the 7th week after treatment.By contrast, no significant changes in serum SEAIC levels were found in the non-treated mice, the serum SEAIC level in the control group maintained moderately high (OD=0. 266±0. 076) till the end of the observation.
CLC Number:
R446.5
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https://www.jsczz.cn/EN/Y1995/V13/I3/189
