Abstract: A total of 166 cases were divided into 3 groups: group A comprised 55,group B 54 and group C 57 cases.Group A received ivermectin 0.1mg/kg orally at a single dore,the cure rates were 100%,3.8% and 50% for ascaris,hookworm and trichuris,infecfions respectively: group B received ivermectin 0.2mg/kg orally at a single dose,the corresponding cure rates were 95.5%,11.8% and 76.5% respectively; group C received pyrantel pamoate 10mg/kg orally at a single dose,the corresponding cure rates were 95.5%,29.6% and 31.6% respectively.Although the cure rates were very low for hookworm infection in both group A and B,however,a number of adult worms of Ancylostoma duodenale and Necator americanus were expelled aster medication; It indicates that ivermectin has some effects on these two species of human hookworm.Side effects were mild and transient in all groups.