Abstract: Using agarose gel electrophoresis, the electrophoretic patterns of four enzymes: ma-late NADP oxidoreducte.se (malic er.zyme) (ME), glucosephosphate isomerase (GPI), phosphogiucomutase (PGM) ar..d hexakinase (HK), were compared and analysed for five strains of Entamoeba histolytica, which had been obtained from patients with acute amebic dysentdry or asymptomatic cyst carrier in Beijing, Tianjin and Fujian Province. The results showed that the electrophoretic patterns of all the five strains of E. histolytica belong to pathogenic zymodeme. zymodeme XIV, which is suggested to be the main pathogenic zymodeme in our country.