IN VIVO SENSITIVITY OF PLASMODIUM FALCIPARUM TO PIPERAQUINE PHOSPHATE ASSAYED IN LINSHUI AND BAISHA COUNTIES, HAINAN PROVINCE

›› 1989, Vol. 7 ›› Issue (3): 163-165.

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IN VIVO SENSITIVITY OF PLASMODIUM FALCIPARUM TO PIPERAQUINE PHOSPHATE ASSAYED IN LINSHUI AND BAISHA COUNTIES, HAINAN PROVINCE

  

  • Received:2017-01-09 Revised:2017-01-09 Online:1989-08-31 Published:2017-01-09

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Abstract: Fifty-three cases of falciparum malaria in Linshui County, Baisha County and Sanya Municipality were treated with piperaquine phosphate at a total dose of 1.5gbase over 3 days in July to December, 1986. The mean defervescence time was 36±20.7h; the mean asexual parasite clearance time was 69.7±20.9h. At 14-28d follow-up lecrudescence was observed with asexual parasitemia in 7 of the 47 cases, showing RI resistance to piperaquine. Gametocytemia was positive in 35 cases (74.5%) during the follow-up period.