Abstract: The efficacy of indirect hemagglutination test using sheep erythrocytes sensitized with crude antigen of adult worms of Onchocerca armillata or Brugia malayi was compared for diagnosis of filariasis in 84 brugian microfilaremia positive patients. It was shown tbat 90.5%(76/84) was positive to antigen of O, armillata, while 92.996(78/84) was positive to antigen of B. malayi, there being no difference of statistical significance (X2 = 0.312, P0.05). In the control test against tne sera of normal persons, the false positive rate of the two antigens was both 7.7%(4/52).It is suggested that O. armillata adult worm may be used as a heteroantigen for diagnosis of filariasis.