Abstract: Daxin County is situated in the south-western part of Guangxi with a population of more than 32.8 thousands. In 1957 the malaria parasite rate were as follows: 22.1% in hilly district where Au. minimus was the mam vector and 4.6% in plain district where An. sinensis was the main vector.Since 1958, DDT indoor residual spraying and drug administration of malaria had been used as control measures. From then till 1979 the malaria morbidity was decreased to 0.2‰ and parasite rate to 0.03%. Malaria was almost eradicated in those districts where An. sinensis was the main vector, but in other districts where Are. minimus was the main vector, a lot of foci still existed. Therefore, we strengthened the antimalaria project in those districts by indoor residual spraying, detection of cases, presumptive trcatment, radical treatment, and tracing of malaria cases. After three years, all the malaria foci were eliminated and the annual blood examination rate of the febril patients was about 11.5%, the annual parasite incidence decreased to 0.1%, quartan malaria and falciparum malaria absent and the tertian malaria has been decreased. In the Encheng village under malaria surveillance from 1980 to 1985, we have examined 11256 febril patients with only two positires and among 903 infants and 6806 inhabitants examined, none had malaria parasite.