Abstract: Juye county is situated in southwest Shandong Province, belonging to the Huanghuai Plain covering an area of 1 230 km2. The total population is 660 thousand. Anopheles sinensis is the malaria vector and epidemic outbreaks of vivax malaria were easy to occur. In order to seek an effective antimalaria strategy, field trials of control measures have been conducted since 1971. Through 15 years' successive antimalaria work the annual incidence dropped from 211.5‰ before the campaign to 0.003‰ in 1985. The results demonstrated that the complex measures with particular emphasis on controlling the source of infection are practicable for malaria control in this area.